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PE 154 - ≥97%(HPLC), high purity , CAS No.1192750-33-6

  • ≥97%(HPLC)
Item Number
P287589
Grouped product items
SKUSizeAvailabilityPrice Qty
P287589-5mg
5mg
In stock
$231.90
P287589-10mg
10mg
In stock
$375.90
P287589-25mg
25mg
In stock
$751.90
P287589-50mg
50mg
In stock
$1,206.90

Discover PE 154 by Aladdin Scientific in ≥97%(HPLC) for only $231.90. Available - in Ligands at Aladdin Scientific. Targets and labels βamyloid plaques in histochemical analysis Tags: .

Basic Description

Synonyms(1Z,N'E)-2-(4-(((E)-(7-(diethylamino)-2,4-dioxochroman-3-ylidene)methyl)amino)phenyl)-N'-(1,2,3,4-tetrahydroacridin-9(10H)-ylidene)acetohydrazonic acid;4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3
Specifications & Purity≥97%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Product description:

PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively)[1]. PE154 can label β-amyloid plaques in histochemical analysis. 


Names and Identifiers

IUPAC Name 2-[4-[[7-(diethylamino)-4-hydroxy-2-oxochromen-3-yl]methylideneamino]phenyl]-N'-(1,2,3,4-tetrahydroacridin-9-yl)acetohydrazide
INCHI InChI=1S/C35H35N5O4/c1-3-40(4-2)24-17-18-27-31(20-24)44-35(43)28(34(27)42)21-36-23-15-13-22(14-16-23)19-32(41)38-39-33-25-9-5-7-11-29(25)37-30-12-8-6-10-26(30)33/h5,7,9,11,13-18,20-21,42H,3-4,6,8,10,12,19H2,1-2H3,(H,37,39)(H,38,41)
InChi Key RSKDYQUBLFFWPM-UHFFFAOYSA-N
Canonical SMILES CCN(CC)C1=CC2=C(C=C1)C(=C(C(=O)O2)C=NC3=CC=C(C=C3)CC(=O)NNC4=C5CCCCC5=NC6=CC=CC=C64)O
WGK Germany 3
PubChem CID 135870290
Molecular Weight 589.68

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
G2311801Certificate of AnalysisMay 25, 2023 P287589
G2311807Certificate of AnalysisMay 25, 2023 P287589
G2311808Certificate of AnalysisMay 25, 2023 P287589
G2311810Certificate of AnalysisMay 25, 2023 P287589
G2311811Certificate of AnalysisMay 25, 2023 P287589
G2311813Certificate of AnalysisMay 25, 2023 P287589
G2311814Certificate of AnalysisMay 25, 2023 P287589
G2311818Certificate of AnalysisMay 25, 2023 P287589

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 29.48, Max Conc. mM: 50

Safety and Hazards(GHS)

WGK Germany 3
RIDADR NONHforallmodesoftransport

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