PE859 - 98%, high purity , CAS No.1402727-29-0

Item Number

P413005

Grouped product items
SKU	Size	Availability	Price
P413005-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
P413005-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90
P413005-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$359.90
P413005-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$619.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 of 0.66 μM and 1.2 μM, respectively.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 of 0.66 μM and 1.2 μM, respectively.

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	6-[(E)-2-[5-[(E)-2-[2-methoxy-4-(pyridin-2-ylmethoxy)phenyl]ethenyl]-1H-pyrazol-3-yl]ethenyl]-1H-indole
INCHI	InChI=1S/C28H24N4O2/c1-33-28-18-26(34-19-25-4-2-3-14-29-25)12-9-22(28)8-11-24-17-23(31-32-24)10-6-20-5-7-21-13-15-30-27(21)16-20/h2-18,30H,19H2,1H3,(H,31,32)/b10-6+,11-8+
InChi Key	AMBZHNVCLPHAKA-NSJFVGFPSA-N
Canonical SMILES	COC1=C(C=CC(=C1)OCC2=CC=CC=N2)C=CC3=CC(=NN3)C=CC4=CC5=C(C=C4)C=CN5
Isomeric SMILES	COC1=C(C=CC(=C1)OCC2=CC=CC=N2)/C=C/C3=CC(=NN3)/C=C/C4=CC5=C(C=C4)C=CN5
PubChem CID	66571561
Molecular Weight	448.52

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
F2417452	Certificate of Analysis	Mar 05, 2024	P413005
F2417467	Certificate of Analysis	Mar 05, 2024	P413005
F2417469	Certificate of Analysis	Mar 05, 2024	P413005
F2417470	Certificate of Analysis	Mar 05, 2024	P413005
F2417471	Certificate of Analysis	Mar 05, 2024	P413005
F2417472	Certificate of Analysis	Mar 05, 2024	P413005
F2417473	Certificate of Analysis	Mar 05, 2024	P413005
F2417474	Certificate of Analysis	Mar 05, 2024	P413005

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Basic Description