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Pepstatin Trifluoroacetate - 10mM in DMSO, high purity , CAS No.P661608(DMSO)

  • 10mM in DMSO
Item Number
P661608
Grouped product items
SKUSizeAvailabilityPrice Qty
P661608-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$55.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempDesiccated,Store at -80°C
Shipped InDry ice
Product Description

Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC 50 s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casei

IC50& Target:IC50: 4.5 nM (Hemoglobin-pepsin), 6.2 nM (Hemoglobin-proctase), 150 nM (Casein-pepsin), 260 nM (Hemoglobin-acid protease), 290 nM (Casein-proctase), 520 nM (Casein-acid protease)

In Vitro:Pepstatin (Pepstatin A) (7 μM; 48 h) affects the intracellular processing of HIV-specific gag protein. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:Pepstatin (Pepstatin A) has a very low toxicity, with LD 50 s of 1090mg/kg, 875mg/kg, 820mg/kg and 450mg/kg for mice, rats, rabbits, and dogs by i.p. route, and > 2000mg/kg for all species by oral route. Pepstatin (0.5-50mg/kg, p.o.) suppresses

Biological Activity:Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC 50 s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casei

Names and Identifiers

Molecular Weight 799.92

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