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Perindopril erbumine - 99%, high purity , Angiotensin-converting enzyme inhibitor, CAS No.107133-36-8, Angiotensin-converting enzyme inhibitor

  • ≥99%
Item Number
P302161
Grouped product items
SKUSizeAvailabilityPrice Qty
P302161-1g
1g
In stock
$72.90
P302161-5g
5g
In stock
$254.90
P302161-25g
25g
In stock
$822.90
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Angiotensin-converting enzyme (ACE) inhibitor

Basic Description

SynonymsPERINDOPRIL ERBUMINE|107133-36-8|ACEON|Perindopril tert-butylamine|McN-A-2833-109|Covapril|Perindopril erbumine [USAN]|S-9490-3|Perindopril (erbumine)|Pederindopril|CHEBI:8025|NSC-758929|DTXSID1044198|UNII-1964X464OJ|1964X464OJ|Perindopril t-Butylamine Sa
Specifications & Purity≥99%
Biochemical and Physiological MechanismsAngiotensin-converting enzyme (ACE) inhibitor (IC50= 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeINHIBITOR
Mechanism of actionAngiotensin-converting enzyme inhibitor

Associated Targets

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC3 Tbio Canalicular multispecific organic anion transporter 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC4 Tchem Multidrug resistance-associated protein 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCB11 Tchem Bile salt export pump 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine
INCHI InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1
InChi Key IYNMDWMQHSMDDE-MHXJNQAMSA-N
Canonical SMILES CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N
Isomeric SMILES CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O.CC(C)(C)N
PubChem CID 441313
Molecular Weight 441.6

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
B2327763Certificate of AnalysisAug 16, 2022 P302161
B2327771Certificate of AnalysisAug 16, 2022 P302161
B2327784Certificate of AnalysisAug 16, 2022 P302161
B2327792Certificate of AnalysisAug 16, 2022 P302161
B2327794Certificate of AnalysisAug 16, 2022 P302161
B2327803Certificate of AnalysisAug 16, 2022 P302161

Chemical and Physical Properties

SolubilitySolvent:ethanol, Max Conc. mg/mL: 22.08, Max Conc. mM: 50
SensitivityMoisture sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

H360:May damage fertility or the unborn child

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

Related Documents

 SDS

 Specification Sheet

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Solution Calculators

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