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Perindopril erbumine - 10mM in Water, high purity , CAS No.107133-36-8

10mM in Water

CAS#: 107133-36-8
Formula: C₂₃H₄₃N₃O₅
Molecular Weight: 441.6
PubChem CID: 441313

Item Number

P420513

Grouped product items
SKU	Size	Availability	Price	Qty
P420513-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$241.90

Angiotensin-converting enzyme (ACE) inhibitor

Basic Description

Synonyms	PERINDOPRIL ERBUMINE\|107133-36-8\|ACEON\|Perindopril tert-butylamine\|McN-A-2833-109\|Covapril\|Perindopril erbumine [USAN]\|S-9490-3\|Perindopril (erbumine)\|Pederindopril\|CHEBI:8025\|NSC-758929\|DTXSID1044198\|UNII-1964X464OJ\|1964X464OJ\|Perindopril t-Butylamine Sa
Specifications & Purity	10mM in Water
Biochemical and Physiological Mechanisms	Angiotensin-converting enzyme (ACE) inhibitor (IC50= 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Associated Targets

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

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ABCC3 Tbio Canalicular multispecific organic anion transporter 2 0 Activities

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ABCC4 Tchem Multidrug resistance-associated protein 4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCB11 Tchem Bile salt export pump 0 Activities

Discover Target: ABCB11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine
INCHI	InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1
InChi Key	IYNMDWMQHSMDDE-MHXJNQAMSA-N
Canonical SMILES	CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N
Isomeric SMILES	CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O.CC(C)(C)N
PubChem CID	441313
Molecular Weight	441.6

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H302:Harmful if swallowed H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help.

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