| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P647814-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $150.90 |
| Synonyms | AKOS040734303 | CS-0003012 | E98879 | MS-29188 | 1039399-17-1 | CYCLOBUTANECARBOXAMIDE, N-ETHYL-3-FLUORO-3-(3-FLUORO-4-(1-PYRROLIDINYLMETHYL)PHENYL)-, TRANS-, 4-METHYLBENZENESULFONATE (1:1) | N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]cy |
|---|---|
| Specifications & Purity | ≥99% |
| Storage Temp | Store at 2-8°C,Desiccated |
| Shipped In | Wet ice |
| Product Description | PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) . Form:Solid IC50& Target:H3 receptor |
| IUPAC Name | N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutane-1-carboxamide;4-methylbenzenesulfonic acid |
|---|---|
| INCHI | InChI=1S/C18H24F2N2O.C7H8O3S/c1-2-21-17(23)14-10-18(20,11-14)15-6-5-13(16(19)9-15)12-22-7-3-4-8-22;1-6-2-4-7(5-3-6)11(8,9)10/h5-6,9,14H,2-4,7-8,10-12H2,1H3,(H,21,23);2-5H,1H3,(H,8,9,10) |
| InChi Key | IKAYTZLLIWAEDV-UHFFFAOYSA-N |
| Canonical SMILES | CCNC(=O)C1CC(C1)(C2=CC(=C(C=C2)CN3CCCC3)F)F.CC1=CC=C(C=C1)S(=O)(=O)O |
| Isomeric SMILES | CCNC(=O)C1CC(C1)(C2=CC(=C(C=C2)CN3CCCC3)F)F.CC1=CC=C(C=C1)S(=O)(=O)O |
| Alternate CAS | 1039399-17-1 |
| PubChem CID | 24862242 |
| Molecular Weight | 494.59 |
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| Solubility | H2O : ≥ 8.4 mg/mL (16.98 mM) |
|---|
