PF-05381941 - 99%, high purity , CAS No.1474022-02-0

Item Number

P647400

Grouped product items
SKU	Size	Availability	Price
P647400-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$270.90
P647400-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$430.90
P647400-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$860.90
P647400-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,380.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	PF-05381941 is a potent dual inhibitor of TAK1/p38α , with IC 50 s of 156 and186 nM, respectively In Vitro PF-05381941 inhibits LPS-stimulated release of TNF-αfrom human peripheralmononuclear (PMN) cells with an IC 50 of 8 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:p38α 186 nM (IC 50 ) TAK1 156 nM (IC 50 )

Canonical SMILES

O=C(NC1=CC=C(OC2=CC=NC=C2)C(C)=C1)NC3=CC(C(C)(C)C)=NN3C4=CC=CC(C#N)=C4

Molecular Weight

466.53

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Basic Description