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PF-05381941 - 10mM in DMSO, high purity , CAS No.1474022-02-0(DMSO)

  • 10mM in DMSO
Item Number
P655015
Grouped product items
SKUSizeAvailabilityPrice Qty
P655015-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$297.90
View related series
MAP3K MAPK/ERK Pathway p38 MAPK

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

PF-05381941 is a potent dual inhibitor of TAK1/p38α , with IC 50 s of 156 and186 nM, respectively

In Vitro

PF-05381941 inhibits LPS-stimulated release of TNF-αfrom human peripheralmononuclear (PMN) cells with an IC 50 of 8 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:p38α 186 nM (IC 50 ) TAK1 156 nM (IC 50 )

Names and Identifiers

Canonical SMILES O=C(NC1=CC=C(OC2=CC=NC=C2)C(C)=C1)NC3=CC(C(C)(C)C)=NN3C4=CC=CC(C#N)=C4
Molecular Weight 466.53

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