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TKL:Tyrosine kinase-like
PF-06426779 , CAS No.P612737, Inhibitor of interleukin 1 receptor associated kinase 4

PF-06426779 , CAS No.P612737, Inhibitor of interleukin 1 receptor associated kinase 4

Item Number

P612737

Grouped product items
SKU	Size	Availability	Price	Qty
P612737-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$667.90
P612737-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	example 189;example 38
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of interleukin 1 receptor associated kinase 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	1-{[(2S,3S,4S)-4-fluoro-3-methyl-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
INCHI	InChI=1S/C17H18FN3O4/c1-8-12(21-16(23)14(8)18)7-25-17-10-6-13(24-2)11(15(19)22)5-9(10)3-4-20-17/h3-6,8,12,14H,7H2,1-2H3,(H2,19,22)(H,21,23)/t8-,12+,14-/m0/s1
InChi Key	GISRWBROCYNDME-PELMWDNLSA-N
Canonical SMILES	COc1cc2c(OC[C@H]3NC(=O)[C@H]([C@H]3C)F)nccc2cc1C(=O)N
Isomeric SMILES	C[C@H]1[C@H](NC(=O)[C@H]1F)COC2=NC=CC3=CC(=C(C=C32)OC)C(=O)N
PubChem CID	118414536

PubChem CID	118414536

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