PF-06454589 - 99%, high purity , CAS No.1527473-30-8

Item Number

P648862

Grouped product items
SKU	Size	Availability	Price
P648862-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$95.90
P648862-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
P648862-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$280.90
P648862-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$420.90
P648862-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$650.90

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Basic Description

Synonyms	PF-06454589\|1527473-30-8\|CHEMBL3393439\|4-[5-(1-methylpyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine\|5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine\|compound 28 [PMID: 25353650]\|GTPL8295\|SCHEMBL15401053\|VNWKCLDQBNSJJO-
Specifications & Purity	99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 can be used for parkinson's disease (PD) research. Form:Solid

Names and Identifiers

IUPAC Name	4-[5-(1-methylpyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine
INCHI	InChI=1S/C14H16N6O/c1-19-8-10(6-18-19)11-7-15-13-12(11)14(17-9-16-13)20-2-4-21-5-3-20/h6-9H,2-5H2,1H3,(H,15,16,17)
InChi Key	VNWKCLDQBNSJJO-UHFFFAOYSA-N
Canonical SMILES	CN1C=C(C=N1)C2=CNC3=C2C(=NC=N3)N4CCOCC4
Isomeric SMILES	CN1C=C(C=N1)C2=CNC3=C2C(=NC=N3)N4CCOCC4
PubChem CID	72706837
Molecular Weight	284.32

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
RIDADR	NONHforallmodesoftransport

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Basic Description