PF-06456384 trihydrochloride - 10mM in DMSO, high purity , CAS No.1834610-75-1(DMSO)

  • 10mM in DMSO
Item Number
P656450
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SKUSizeAvailabilityPrice Qty
P656450-1ml
1ml
Available within 8-12 weeks(?)
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$164.90
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Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsPF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 trihydrochloride can be used for parkinson's disease (PD) resea
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

PF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 trihydrochloride can be used for parkinson's disease (PD) research.

Names and Identifiers

Canonical SMILES C1CNCCC1CCNCC2=NC=CC(=C2)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(F)(F)F)OC5=C(C=C(C=C5)S(=O)(=O)NC6=NC=NS6)C#N.Cl.Cl.Cl
Molecular Weight 829.18

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