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PGS-IN-1 - 99%, high purity , CAS No.102271-49-8

  • ≥99%
Item Number
P649115
Grouped product items
SKUSizeAvailabilityPrice Qty
P649115-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$240.90
P649115-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$480.90
P649115-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$816.90
P649115-20mg
20mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,440.90

Basic Description

Specifications & Purity99%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC 50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC 50 of 1.05 μM.

In Vitro

The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:5-Lipoxygenase 1.05 μM (IC 50 )

Names and Identifiers

Canonical SMILES O=C1OCC/C1=C\\C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Molecular Weight 302.41

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators