The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Phenamil , CAS No.2038-35-9, Channel blocker of TRPP2
an amiloride analog that irreversibly blocks amiloride-sensitive Na+channels.
Basic Description Synonyms Phenamil|phenylamil|2038-35-9|CHEMBL211502|CHEBI:34919|CID 5353878|3,5-diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide|2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-|Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-( Specifications & Purity Moligand™ Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type CHANNEL BLOCKER Mechanism of action Channel blocker of TRPP2 Product Description Phenamil is an amiloride analog. Irreversibly blocks ENaC (amiloride-sensitive Na|+|channels).
Names and Identifiers IUPAC Name 3,5-diamino-6-chloro-N-(N'-phenylcarbamimidoyl)pyrazine-2-carboxamide INCHI InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21) InChi Key NIOHELZQFBGCEO-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)N=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N Isomeric SMILES C1=CC=C(C=C1)N=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N WGK Germany 3 PubChem CID 135403792 Molecular Weight 305.72
Chemical and Physical Properties Solubility Soluble in water (partly), DMSO (15 mg/ml), and 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (2.5 mg/ml). Insoluble in 0.1 M HCl, and dilute aquueous acid . Refractive Index n20D1.76 (Predicted) Boil Point(°C) 621.7° C at 760 mmHg (Predicted) (tautomer) Melt Point(°C) 258-260° C
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
