Phloxine B - ≥97.0 %, high purity , CAS No.18472-87-2

Item Number
P102690
Grouped product items
SKUSizeAvailabilityPrice Qty
P102690-5g
5g
In stock
$68.90
P102690-25g
25g
In stock
$259.90

Basic Description

SynonymsAcid red 92 | 18472-87-2 | Phloxin B | Cyanosine | Eosine bluish | Eosin Blue | Eosine Blue | Cyanosin B | C.I. Acid Red 92 | Phloxine P | sodium 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-bis(olate) | Water Pink 2 | Daiwa Red 45
Specifications & Purity≥97.0 %
Shipped InNormal
Gradehigh-purity
Product Description

Phloxine B is a fluorescein dye which is known to inhibit the enzyme UDP-glucuronosyltransferase (UGT), the main catalyst for the glucuronidation of 7-HC. Additionally, Phloxine B is reported to be a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. As a photoactive dye, Phloxine B is reported to have efficacy against gram-positive organisms. Phloxine B has also been utilized in a study investigating the visible light-induced photodegradation kinetics when coated onto silica TLC plates and in solution. The rapid photodegradation of Phloxine B via visible light exposure was noted and the phototoxicity of the remaining residues were also reported to be decreased.
A fluorescein photoactive dye

Names and Identifiers

IUPAC Name disodium;2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
INCHI InChI=1S/C20H4Br4Cl4O5.2Na/c21-5-1-3-17(9(23)15(5)29)32-18-4(2-6(22)16(30)10(18)24)20(3)8-7(19(31)33-20)11(25)13(27)14(28)12(8)26;;/h1-2,29-30H;;/q;2*+1/p-2
InChi Key OOYIOIOOWUGAHD-UHFFFAOYSA-L
Canonical SMILES C1=C2C(=C(C(=C1Br)[O-])Br)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)Br)[O-])Br.[Na+].[Na+]
Isomeric SMILES C1=C2C(=C(C(=C1Br)[O-])Br)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)Br)[O-])Br.[Na+].[Na+]
WGK Germany 2
RTECS LM5900000
PubChem CID 6433718
Molecular Weight 829.63
Beilstein 3887100
Reaxy-Rn 6364882

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
L2320086Certificate of AnalysisDec 25, 2023 P102690
A2405370Certificate of AnalysisJul 03, 2023 P102690
C2427042Certificate of AnalysisJul 03, 2023 P102690
F2326193Certificate of AnalysisJul 03, 2023 P102690
F2326210Certificate of AnalysisJul 03, 2023 P102690
B2301228Certificate of AnalysisSep 14, 2022 P102690
B2303119Certificate of AnalysisSep 14, 2022 P102690
B2303534Certificate of AnalysisSep 14, 2022 P102690
B2303541Certificate of AnalysisSep 14, 2022 P102690
D2307371Certificate of AnalysisSep 14, 2022 P102690

Chemical and Physical Properties

SolubilitySoluble in water (1 mg/ml) (clear red solution).,

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H373:Causes damage to organs through prolonged or repeated exposure

H412:Harmful to aquatic life with long lasting effects

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS LM5900000
Reaxy-Rn 6364882

Related Documents

Citations of This Product

1. Hong Yi, Zhou Zhou, Yu Lingzi, Jiang Keyang, Xia Jiamiao, Mi Yuling, Zhang Caiqiao, Li Jian.  (2021)  Lactobacillus salivarius and Lactobacillus agilis feeding regulates intestinal stem cells activity by modulating crypt niche in hens.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  105  (23): (8823-8835).  [PMID:34708278]

References

1. Hong Yi, Zhou Zhou, Yu Lingzi, Jiang Keyang, Xia Jiamiao, Mi Yuling, Zhang Caiqiao, Li Jian.  (2021)  Lactobacillus salivarius and Lactobacillus agilis feeding regulates intestinal stem cells activity by modulating crypt niche in hens.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  105  (23): (8823-8835).  [PMID:34708278]

Solution Calculators