Phosphorus tribromide (PBr3) is commonly used in Hell-Volhard-Zelinsky halogenation for the α-bromination of carboxylic acids to form the corresponding acyl bromide. It is also useful for the conversion of primary and secondary alcohols to alkyl bromides.
Phosphorus tribromide may be used as a reagent:
· In a novel protocol for synthesizing 7-ethoxy-1-(p-ethylphenoxy)-3,7-dimethyl-2-octene, a synthetic juvenile hormone mimic of trans,trans,cis-10,11-epoxy-7-ethyl-3,11-dimethyltrideca-2,6-dienoate.
· To synthesize 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring.
· To synthesize 1-Bromoundec-1-ene from 10-undecen-1-ol.
1.Rahul A Patil,Mohsen Talebi,Alain Berthod,Daniel W Armstrong. (2018-01-31) Dicationic ionic liquid thermal decomposition pathways.. Analytical and bioanalytical chemistry, 410 ((19)):(4645-4655). [PMID:29380017]
2.Jiang Yan,Qinglei Meng,Xiaojun Shen,Bingfeng Chen,Yang Sun,Junfeng Xiang,Huizhen Liu,Buxing Han. (2020-11-08) Selective valorization of lignin to phenol by direct transformation of Csp2-Csp3 and C-O bonds.. Science advances, 6 ((45)):[PMID:33158871]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
C2407238