PI3K/mTOR Inhibitor-2 - 10mM in DMSO, high purity , CAS No.1848242-58-9(DMSO)

Item Number

P655747

• Specifications & Purity: 10mM in DMSO
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads

Product Description

PI3K/mTOR Inhibitor-2 is a potent dual pan- PI3K / mTOR inhibitor with IC 50 s of 3.4/34/16/1 nM for PI3Kα / PI3Kβ / PI3Kδ / PI3Kγ and 4.7 nM for mTOR Antitumor activity

In Vitro

PI3K/mTOR Inhibitor-2 (Compound 31) inhibits p-AKT and p-p70s6k in MCF-7 cells with IC 50 s of 11.6 and 89.2 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:PI3Kα 3.4 nM (IC 50 ) PI3Kβ 34 nM (IC 50 ) PI3Kδ 16 nM (IC 50 ) PI3Kγ 1 nM (IC 50 ) mTOR 4.7 nM (IC 50 )