PI4KIIIbeta-IN-10 - 99%, high purity , CAS No.1881233-39-1

Item Number

P651260

• Synonyms: PI4KIIIbeta-IN-10|1881233-39-1|N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide|CHEMBL3786230|N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide|PI4KIII beta inhi
• Specifications & Purity: ≥99%
• Biochemical and Physiological Mechanisms: PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC 50 of 3.6 nM.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC 50 of 3.6 nM.

In Vitro

PI4KIIIbeta-IN-10 (Compound 10) is a potent PI4KIIIβ inhibitor with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC 50 ~1 µM), PI3Kα (~10 µM), and PI4KIIIα (~3 µM), and <20% inhibition at concentrations up to 20 µM for PI4K2α, PI4K2β, and PI3Kβ. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:PI4KIIIβ 3.6 nM (IC 50 ) PI4KIIIα 3 μM (IC 50 ) PI3Kδ 720 nM (IC 50 ) PI3KC2γ 1 μM (IC 50 ) PI3Kα 10 μM (IC 50 ) PI3Kγ 20 μM (IC 50 )