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PI4KIIIbeta-IN-9 - 98%, high purity , CAS No.1429624-84-9

  • ≥98%
Item Number
P412989
Grouped product items
SKUSizeAvailabilityPrice Qty
P412989-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$82.90
P412989-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$246.90
P412989-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$368.90
P412989-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$621.90
P412989-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$884.90
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Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsPI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ with IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50 of 152 nM and 1046 nM, respectively.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ with IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50 of 152 nM and 1046 nM, respectively.

Associated Targets

PIK3CG Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3CA Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3CB Tchem Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3CD Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3C3 Tchem Phosphatidylinositol 3-kinase catalytic subunit type 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3C2G Tchem Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PI4K2B Tbio Phosphatidylinositol 4-kinase type 2-beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PI4K2A Tbio Phosphatidylinositol 4-kinase type 2-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]cyclopentanecarboxamide
INCHI InChI=1S/C23H25N3O5S2/c1-14-21(32-23(24-14)25-22(28)15-5-3-4-6-15)16-7-12-19(31-2)20(13-16)33(29,30)26-17-8-10-18(27)11-9-17/h7-13,15,26-27H,3-6H2,1-2H3,(H,24,25,28)
InChi Key KAXNDTMKFONXJM-UHFFFAOYSA-N
Canonical SMILES CC1=C(SC(=N1)NC(=O)C2CCCC2)C3=CC(=C(C=C3)OC)S(=O)(=O)NC4=CC=C(C=C4)O
Isomeric SMILES CC1=C(SC(=N1)NC(=O)C2CCCC2)C3=CC(=C(C=C3)OC)S(=O)(=O)NC4=CC=C(C=C4)O
PubChem CID 71533728
Molecular Weight 487.6

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Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2410481Certificate of AnalysisMay 27, 2024 P412989
G2410519Certificate of AnalysisMay 27, 2024 P412989
G2410521Certificate of AnalysisMay 27, 2024 P412989
G2410522Certificate of AnalysisMay 27, 2024 P412989
G2410523Certificate of AnalysisMay 27, 2024 P412989
G2410524Certificate of AnalysisMay 27, 2024 P412989
G2410529Certificate of AnalysisMay 27, 2024 P412989
G2410530Certificate of AnalysisMay 27, 2024 P412989
G2410531Certificate of AnalysisMay 27, 2024 P412989
G2410534Certificate of AnalysisMay 27, 2024 P412989

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