Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P129680-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $68.90 | |
P129680-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $107.90 | |
P129680-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $345.90 | |
P129680-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,557.90 | |
P129680-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $5,605.90 |
Ca 2+ channel sensitizer. Selective PDE3 inhibitor.
Synonyms | BDBM50282617 | EN300-27067685 | KS-1280 | PIMOBENDAN (EP IMPURITY) | DTXSID8048280 | PIMOBENDAN [USP-RS] | UD-CG 115 | PIMOBENDAN [WHO-DD] | CHEBI:32003 | Pimobendan,USP | Pimobendanum [INN-Latin] | (-)-UD-CG 115BS | d-Pimobendan | pimobendane | AKOS01585 |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Ca 2+ channel sensitizer. Selective PDE3 inhibitor. Inhibits platelet aggregation. Shows antithrombotic, antihypertensive, potent inotropic and vasodilatory effects in vivo. Orally active. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. |
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IUPAC Name | 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one |
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INCHI | InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24) |
InChi Key | GLBJJMFZWDBELO-UHFFFAOYSA-N |
Canonical SMILES | CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC |
Isomeric SMILES | CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC |
PubChem CID | 4823 |
Molecular Weight | 334.37 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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![]() | Certificate of Analysis | Jan 20, 2023 | P129680 |
Solubility | DMSO 67 mg/mL (200 mM); 水 <1 mg/mL (<1 mM) ; Ethanol 5 mg/mL (14 mM) |
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Sensitivity | Air Sensitive,Heat Sensitive |
Melt Point(°C) | 249 °C(dec.) |
Pictogram(s) | GHS06, GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H412:Harmful to aquatic life with long lasting effects H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed H332:Harmful if inhaled H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. |