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PKUMDL-LC-101-D04 - ≥98.0%, high purity , CAS No.2143896-83-5

Item Number

P646948

Grouped product items
SKU	Size	Availability	Price	Qty
P646948-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
P646948-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,050.90

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Basic Description

Specifications & Purity	≥98.0%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator ( pEC 50 =4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts. Form:Solid

IUPAC Name	1-[4-(2-aminoethylsulfamoyl)phenyl]-3-cyclopentylthiourea;hydrochloride
INCHI	InChI=1S/C14H22N4O2S2.ClH/c15-9-10-16-22(19,20)13-7-5-12(6-8-13)18-14(21)17-11-3-1-2-4-11;/h5-8,11,16H,1-4,9-10,15H2,(H2,17,18,21);1H
InChi Key	FELDRJSFLBINQS-UHFFFAOYSA-N
Canonical SMILES	C1CCC(C1)NC(=S)NC2=CC=C(C=C2)S(=O)(=O)NCCN.Cl
Isomeric SMILES	C1CCC(C1)NC(=S)NC2=CC=C(C=C2)S(=O)(=O)NCCN.Cl
PubChem CID	155543553
Molecular Weight	378.94

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Solubility	DMSO : 250 mg/mL (659.74 mM; Need ultrasonic)

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