PKUMDL-LC-101-D04 - ≥98.0%, high purity , CAS No.2143896-83-5

  • ≥98%
Item Number
P646948
Grouped product items
SKUSizeAvailabilityPrice Qty
P646948-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$550.90
P646948-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,050.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsPKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator ( pEC 50 =4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator ( pEC 50 =4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts.

Form:Solid

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-[4-(2-aminoethylsulfamoyl)phenyl]-3-cyclopentylthiourea;hydrochloride
INCHI InChI=1S/C14H22N4O2S2.ClH/c15-9-10-16-22(19,20)13-7-5-12(6-8-13)18-14(21)17-11-3-1-2-4-11;/h5-8,11,16H,1-4,9-10,15H2,(H2,17,18,21);1H
InChi Key FELDRJSFLBINQS-UHFFFAOYSA-N
Canonical SMILES C1CCC(C1)NC(=S)NC2=CC=C(C=C2)S(=O)(=O)NCCN.Cl
Isomeric SMILES C1CCC(C1)NC(=S)NC2=CC=C(C=C2)S(=O)(=O)NCCN.Cl
PubChem CID 155543553
Molecular Weight 378.94

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 250 mg/mL (659.74 mM; Need ultrasonic)

Related Documents

Solution Calculators