PluriSIn #1 (NSC 14613) - ≥98%, high purity , CAS No.91396-88-2

Item Number

P129781

Grouped product items
SKU	Size	Availability	Price
P129781-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$64.90
P129781-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$195.90
P129781-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$352.90

Selective SCD1 inhibitor

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Basic Description

Synonyms	PluriSln 1\|91396-88-2\|N'-phenylisonicotinohydrazide\|plurisin 1\|N'-phenylpyridine-4-carbohydrazide\|NSC 14613\|PluriSIn #1\|PluriSIn #1 (NSC 14613)\|PluriSln 1(NSC 14613)\|4-Pyridinecarboxylic acid 2-phenylhydrazide\|PluriSln-1 (NSC 14613)\|C12H11N3O\|MFCD02344904
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture by selectively inducing apoptosis in these cells. Additionally, pluriSln 1 induces endoplasmic
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs A SCD1 inhibitor and apoptosis inducer.

Names and Identifiers

IUPAC Name	N'-phenylpyridine-4-carbohydrazide
INCHI	InChI=1S/C12H11N3O/c16-12(10-6-8-13-9-7-10)15-14-11-4-2-1-3-5-11/h1-9,14H,(H,15,16)
InChi Key	HUDWXDLBWRHCKO-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2
Isomeric SMILES	C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2
WGK Germany	3
PubChem CID	225362
Molecular Weight	213.24

Certificates

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Lot Number	Certificate Type	Date	Item
F1510062	Certificate of Analysis	Jan 19, 2023	P129781

Solubility

DMSO 43 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

Sensitivity

Heat Sensitive

Melt Point(°C)

189 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation H302:Harmful if swallowed
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	3

Solution Calculators

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Basic Description