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Poloxamer 407 - purified, non-ionic, high purity , CAS No.9003-11-6

140 Citations
  • purified, non-ionic
Item Number
P434419
Grouped product items
SKUSizeAvailabilityPrice Qty
P434419-50g
50g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$60.90
P434419-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$183.90
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Basic Description

SynonymsEmkalyx L101 | Pluronic F 68 | Regulaid | Magcyl | Pluronic L 64 | Pronon 204 | Teric PE60 | Pluronic F 38 | Pluronic L | Teric PE40 | Pluronic L44 | Pluronic P-75 | Rokopol 30P9 | Slovanik 630 | Hydrowet | Pluronic 31R2 | Pluronic L 68 | Monolan PB | Plu
Specifications & Puritypurified, non-ionic
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Poloxamer 407 is a water-soluble, non-ionic surfactant with low toxicity and good solubilizing capacity. This triblock copolymer is composed of a hydrophobic residue of polyoxypropylene (POP) flanked by two hydrophilic units of polyoxyethylene (POE).

Application：

as an inhibitor of lipoprotein lipase activity to assess hepatic very-low-density lipoprotein (VLDL)- triglyceride (TG) secretion in mice；for VLDL secretion assay in mice；to intraperitoneally inject the mice by dissolving in phosphate buffer saline (PBS) for hepatic triglyceride production  

Names and Identifiers

IUPAC Name 2-methyloxirane;oxirane
INCHI InChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChi Key RVGRUAULSDPKGF-UHFFFAOYSA-N
Canonical SMILES CC1CO1.C1CO1
Isomeric SMILES CC1CO1.C1CO1
Alternate CAS 691397-13-4
PubChem CID 24751

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
E2427402Certificate of AnalysisNov 03, 2023 P434419
K2301427Certificate of AnalysisNov 03, 2023 P434419
K2301428Certificate of AnalysisNov 03, 2023 P434419
K2301429Certificate of AnalysisNov 03, 2023 P434419
K2301462Certificate of AnalysisNov 03, 2023 P434419

Chemical and Physical Properties

Solubilitysoluble, clear, colorless
Refractive Index1.459
Boil Point(°C)> 149 °C
Melt Point(°C)55 - 61 °C

Safety and Hazards(GHS)

Signal Warning

Related Documents

 SDS

 Specification Sheet

Citations of This Product

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17. Xiao Han, Jia-Horng Lin, Xia-Yun Zhang, Hao-Kai Peng, Li-Yan Liu, Lu Zhang, Ching-Wen Lou, Bing-Chiuan Shiu, Ting-Ting Li.  (2024)  PMD/TiO2 gel/aramid fabric synergistically toughened to build soft composites with high puncture resistance and rapid self-healing.  COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING,  176  (18): (107858).  [PMID:21949239]
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19. Hongli Zhao, Tong Feng, Yue Feng, Xue Liu, Minbo Lan, Shaohua Zuo.  (2024)  Ordered hollow mesoporous carbon cubes loaded with Au nanoparticles for high-performance electrochemical detection of hexavalent chromium.  SENSORS AND ACTUATORS B-CHEMICAL,  399  (18): (134757).  [PMID:26074468]
20. Anqi Lu, Xiaokang Xiang, Ming Lei, Shuangshuang Huang, Bingbing Liang, Siyu Zhao, Lihua Zhu, Heqing Tang.  (2023)  Highly efficient catalytic transfer hydrogenation for the conversion of nitrobenzene to aniline over PdO/TiO2: The key role of in situ switching from PdO to Pd.  Journal of Environmental Sciences,    (2):   [PMID:8610169]
21. Weigao Han, Fang Dong, Weiliang Han, Xiaosheng Huang, Zhicheng Tang.  (2023)  Constructing mesoporous FeAlOx based catalysts through framework-confined strategy with superior performance for the oxidative dehydrogenation of 1-butene with CO2.  CHEMICAL ENGINEERING JOURNAL,  475  (1): (146432).  [PMID:12560483]
22. Chi Jiang, Mengmeng Zhang, Yingfei Hou.  (2023)  Thin-Film Composite Membrane with Porous Interlayer Composed of Dendritic Mesoporous Silica Nanoparticles for Enhanced Nanofiltration.  Polymers,  15  (19): (3912).  [PMID:37835961]
23. Jietao Liu, Shenye Qu, Tao Wang, Bin Yang, Xiang Liu, Gaoxue Wang, Pengfei Li, Qing Yu, Fei Ling.  (2024)  Nanosuspensions as an approach for improved solubility and anti-Ichthyophthirius multifiliis activity of magnolol.  AQUACULTURE,  579  (15): (740133).  [PMID:10397721]
24. Wang Zhaoyang, Li Zekai, Shi Yuehua, Zeng Leyong.  (2023)  Mesoporous polydopamine delivery system for intelligent drug release and photothermal-enhanced chemodynamic therapy using MnO2 as gatekeeper.  Regenerative Biomaterials,    (1):   [PMID:37936892]
25. Tianheng Wang, XueBao Liu, Jing Luo, Guanqing Sun, Ren Liu.  (2023)  Reduction of interfacial polycondensation self-limitation through solvent swelling to dynamically modulate shell thickness and structure of microcapsules.  POLYMER,  285  (126369).  [PMID:15107860]
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28. Zi-Chun Fan, Xiang Bai, Xian-Yong Wei, Xing Fan, Yierxiati Dilixiati, Zhuang Li, Qian-Qian Kong, Ji Zhao, Li Li, Jia-Hao Li, Zhi-Min Zong.  (2023)  Electrochemical detection of p-nitrophenol over nickel nanoparticles supported on Longquan lignite-derived mesoporous carbon fabricated by hard template method.  MICROCHEMICAL JOURNAL,  194  (27): (109354).  [PMID:12397079]
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43. Yangyang Wang, Xin Wen, Xiaojing Dong, Chen Xu, Wenguang Ma, Yiqiang Sun, Bo Xu, Cuncheng Li.  (2023)  Electronic modulation of heterostructured MoOx supported Ru as robust bifunctional catalyst for overall water splitting.  CRYSTENGCOMM,  25  (31): (4480-4486).  [PMID:]
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47. Rui Xu, Junjie Xiong, Changping Shi, Dan Liu, Man Yang, Zhenxu Wei, Yang Nie, Junzhuo Li, Yin-an Ming.  (2023)  Nickel-doped mesoporous manganese oxides for enhanced peroxymonosulfate-based oxidation of tetracycline hydrochloride: Performance and mechanism.  MICROPOROUS AND MESOPOROUS MATERIALS,  360  (112702).  [PMID:]
48. Lizhong Wang, Guochen Jiang, Dongyu Zhu, Ze Tian, Changhao Chen, Xinyu Hu, Rui Peng, Daizhou Li, Hongjun Zhang, Huanyu Zhao, Peixun Fan, Minlin Zhong.  (2023)  Self-Driven Droplet Motions Below their Icing Points.  Small,  19  (41): (2302339).  [PMID:37312674]
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50. Sabarinathan Ravichandran, Narayanamoorthy Bhuvanendran, Shuhua Hao, Shirong Sun, Thandavarayan Maiyalagan, Huaneng Su, Xihong Zu, Wenli Zhang.  (2023)  PANI-SnO2 nanorods decorated with Pdx-Niy nanoparticles for improved electrooxidation of methanol with extended durability.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  673  (131833).  [PMID:]
51. Maocai Li, Qiyuan Dai, Shuangli Zhu, Qi Feng, Zhihao Qin, Huichang Gao, Xiaodong Cao.  (2023)  An ultrafast water absorption composite cryogel containing Iron-doped bioactive glass with rapid hemostatic ability for non-compressible and coagulopathic bleeding.  CHEMICAL ENGINEERING JOURNAL,  469  (143758).  [PMID:]
52. He Zhao, Ling Zhang, Tianbo Deng, Chunzhong Li.  (2023)  High-performance sensing, breathable, and biodegradable integrated wearable sweat biosensors for a wireless glucose early warning system.  Journal of Materials Chemistry A,  11  (23): (12395-12404).  [PMID:]
53. Lu Chen, Gaojie Chen, Kang Hu, Lianxu Chen, Zhiyong Zeng, Bin Li, Guohua Jiang, Yang Liu.  (2023)  Combined photothermal and photodynamic therapy enhances ferroptosis to prevent cancer recurrence after surgery using nanoparticle-hydrogel composite.  CHEMICAL ENGINEERING JOURNAL,  468  (143685).  [PMID:]
54. Qianli Li, Yi Hou, Pinyin Cao, Ruiye Bi, Songsong Zhu.  (2023)  Near-Infrared Light-Activated Mesoporous Polydopamine for Temporomandibular Joint Osteoarthritis Combined Photothermal-Chemo Therapy.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (10): (9055).  [PMID:37240401]
55. Lianfu Wang, Manxiang Wu, Yuning Pan, Dong Xie, Chengyuan Hong, Jianbin Li, Xuehua Ma, Huachun Xu, Huayu Li, Tianxiang Chen, Aiguo Wu, Qiang Li.  (2023)  Sequential targeting biomimetic nano platform for enhanced mild photothermal therapy and chemotherapy of tumor.  Computational and Structural Biotechnology Journal,  21  (2780).  [PMID:37181660]
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57. Xiao Chuyao, Li Genyun, Li Xiaoyue, Wang Dan, Wu Ya, Sun Minghui, Huang Jiangeng, Si Luqin.  (2023)  A topical thermosensitive hydrogel system with cyclosporine A PEG-PCL micelles alleviates ulcerative colitis induced by TNBS in mice.  Drug Delivery and Translational Research,    (1-16).  [PMID:37060530]
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62. Jiahui Yan, Jingwen Zhang, Yanan Wang, Hong Liu, Xueping Sun, Aixin Li, Pengfei Cui, Liangmin Yu, Xuefeng Yan, Zhiyu He.  (2023)  Rapidly Inhibiting the Inflammatory Cytokine Storms and Restoring Cellular Homeostasis to Alleviate Sepsis by Blocking Pyroptosis and Mitochondrial Apoptosis Pathways.  Advanced Science,  10  (14): (2207448).  [PMID:36932048]
63. Yi Liu, Haolu Hu, Jiamin Zheng, Fei Xie, Huayu Gu, Sadegh Rostamnia, Fangfang Pan, Xiao Liu, Lizhi Zhang.  (2023)  Interfacial engineering enables surface lattice oxygen activation of SmMn2O5 for catalytic propane combustion.  APPLIED CATALYSIS B-ENVIRONMENTAL,  330  (122649).  [PMID:]
64. Zhenwei Wu, Kun Zhang, Jiaming Sun, Chunhui Ma, Sha Luo, Wei Li, Shouxin Liu.  (2023)  Kinetics-Controlled Synthesis of Ordered Mesoporous Carbon Single Crystals from Liquefied Wood.  ADVANCED FUNCTIONAL MATERIALS,  33  (20): (2213852).  [PMID:]
65. Yanyu Li, Xiaoyue Zhang, Jinglin Shen, Wei Qi.  (2023)  A Colorimetric Paper Sensor Based on Self-assembled Nanocomposite Pd−Pt@hemin-rGO/CNTs-COOH for the Detection of H2O2.  ChemNanoMat,  9  (5): (e202200569).  [PMID:]
66. Ya Liu, Yaqi Ren, Jing Huang, Hongsheng Lu, Zhiyu Huang, Li Wang.  (2023)  A mechanically strong shape-memory organohydrogel based on dual hydrogen bonding and gelator-induced solidification effect.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  665  (131175).  [PMID:]
67. Eunshinae Cho, Yi Qiao, Changan Chen, Junjie Xu, Jiangyu Cai, Yamin Li, Jinzhong Zhao.  (2023)  Injectable FHE+BP composites hydrogel with enhanced regenerative capacity of tendon-bone interface for anterior cruciate ligament reconstruction.  Frontiers in Bioengineering and Biotechnology,  11  (1117090).  [PMID:36911205]
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