Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(D,L-lactide-co-glycolide) (PLGA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.
1.Miles A Miller, Yao-Rong Zheng, Suresh Gadde, Christina Pfirschke, Harshal Zope, Camilla Engblom, Rainer H Kohler, Yoshiko Iwamoto, Katherine S Yang, Bjorn Askevold, Nagesh Kolishetti, Mikael Pittet, Stephen J Lippard, Omid C Farokhzad, Ralph Weissleder,. (2015-10-28) Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.. Nature communications, ( 8692-8692 ). [PMID:26503691]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.