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Poly(D,L-lactide-co-glycolide)(85/15)-b-poly(ethylene glycol)-carboxylic acid - 5k-13k, high purity

  • 5k-13k
Item Number
P466748
Grouped product items
SKUSizeAvailabilityPrice Qty
P466748-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,009.90

Basic Description

Specifications & Purity5k-13k
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Description

Biocompatible, amphiphilicblockcopolymer composed of a hydrophilic PEGblockand a hydrophobic Poly(lactide-co-glycolide) (PLGA)block, functionalized with a terminal carboxylic acid. These materials have been used in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymerblock. Additionally, the ratio of lactide to glycolide can be tuned to control rate of degradation. Carboxylic acid termination allows for facile further chemical modification of these materials.

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Related Documents

References

1. Miles A Miller, Yao-Rong Zheng, Suresh Gadde, Christina Pfirschke, Harshal Zope, Camilla Engblom, Rainer H Kohler, Yoshiko Iwamoto, Katherine S Yang, Bjorn Askevold, Nagesh Kolishetti, Mikael Pittet, Stephen J Lippard, Omid C Farokhzad, Ralph Weissleder,.  (2015-10-28)  Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug..  Nature communications,    ( 8692-8692 ).  [PMID:26503691]

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