Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It facilitates the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. Application Poly(ethylene glycol) (PEG) has been used to dissolve JC-124, nucleotide-binding domain, leucine rich family pyrin containing 3 gene (NLRP3) inflammasome inhibitor and solubilize CoQ10, a mitochondrial coenzyme Q4.
Names and Identifiers
PH
5.5-7.0 (25 °C, 50 mg/mL in H2O)
Canonical SMILES
C(CO)O
WGK Germany
1
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1.J Huang, Z Chen, C Wen, T Ling, Z Chen. (2022) Thermally assisted 3D printing of bio-polymer with high solute loading with improved mechanical properties. Additive Manufacturing, (59A):(103088). [PMID:]
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