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Poly(ethylene glycol)-block-polyethyleneimine - PEG Mₙ 750, PEI Mₙ 15k, high purity

  • PEG Mₙ 750, PEI Mₙ 15k
Item Number
P475597
Grouped product items
SKUSizeAvailabilityPrice Qty
P475597-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$707.90
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Basic Description

Specifications & PurityPEG Mₙ 750, PEI Mₙ 15k
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Description

Gene therapy using polymeric nonviral vectors promises considerable advances in the treatment of many genetic and acquired diseases due to the carrier safety and low immunogenicity profiles. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
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Related Documents

References

1. Pallab Banerjee, Ralph Weissleder, Alexei Bogdanov,.  (2006-01-19)  Linear polyethyleneimine grafted to a hyperbranched poly(ethylene glycol)-like core: a copolymer for gene delivery..  Bioconjugate chemistry,  17  ((1)): ( 125-131 ).  [PMID:16417260]

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