Usually used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.
Application:
Cell fusion induced by polyethylene glycol(PEG) has become a standard method in somatic cell genetics. PEG promoted cell fusion is involved in the production of hybridoma cells.
Names and Identifiers
Canonical SMILES
C(CO)O
WGK Germany
1
Certificates
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1.D D Smyth,P I Polimeni. (1990-02-01) Drag-reducing polymers: a novel class of diuretic and natriuretic compounds.. Cardiovascular drugs and therapy, 4 ((1)):(297-300). [PMID:2285623]
2.P I Polimeni,B T Ottenbreit. (1989-09-01) Hemodynamic effects of a poly(ethylene oxide) drag-reducing polymer, Polyox WSR N-60K, in the open-chest rat.. Journal of cardiovascular pharmacology, 14 ((3)):(374-380). [PMID:2476615]
3.Mark A Rice,Kendall R Waters,Kristi S Anseth. (2008-09-17) Ultrasound monitoring of cartilaginous matrix evolution in degradable PEG hydrogels.. Acta biomaterialia, 5 ((1)):(152-161). [PMID:18793879]
4.M Patel Geeta,M Patel Madhabhai. (2009-05-20) Design and in vitro evaluation of a novel vaginal drug delivery system based on gelucire.. Current drug delivery, 6 ((2)):(159-165). [PMID:19450222]
5.Idalis Villanueva,Courtney A Weigel,Stephanie J Bryant. (2009-06-11) Cell-matrix interactions and dynamic mechanical loading influence chondrocyte gene expression and bioactivity in PEG-RGD hydrogels.. Acta biomaterialia, 5 ((8)):(2832-2846). [PMID:19508905]
6.Thomas McNerney,Anne Thomas,Anna Senczuk,Krista Petty,Xiaoyang Zhao,Rob Piper,Juliane Carvalho,Matthew Hammond,Satin Sawant,Jeanine Bussiere. (2015-02-24) PDADMAC flocculation of Chinese hamster ovary cells: enabling a centrifuge-less harvest process for monoclonal antibodies.. mAbs, 7 ((2)):(413-428). [PMID:25706650]
7.Pengfei Han, Yuewu Zhu, Jin Liu. (2015) An all-solid-state lithium ion battery electrolyte membrane fabricated by hot-pressing method. Journal of Power Sources, 284 (284):(459-465). [PMID:]
8.J Huang, Z Chen, C Wen, T Ling, Z Chen. (2022) Thermally assisted 3D printing of bio-polymer with high solute loading with improved mechanical properties. Additive Manufacturing, (59A):(103088). [PMID:]
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