pp60v-src Autophosphorylation Site, Tyrosine Kinase Substrate - >97%, high purity , CAS No.81493-98-3

  • ≥97%
Item Number
P332708
Grouped product items
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P332708-1mg
1mg
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$89.90

a tyrosine kinase substrate with ability to phosphorylate

Basic Description

Synonymspp60v-src Autophosphorylation Site, Tyrosine Kinase Substrate | DTXSID30648691 | N~5~-(Diaminomethylidene)ornithyl-N~5~-(diaminomethylidene)ornithylleucylisoleucyl-alpha-glutamyl-alpha-aspartylasparaginyl-alpha-glutamyltyrosylthreonylalanyl-N~5~-(diaminom
Specifications & Purity>97%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

pp60v-src Autophosphorylation Site, Tyrosine Kinase Substrate Protein is a tyrosine kinase substrate with the ability to phosphorylate. Residues 2-12 in this peptide correspond to the sequence of the reported site of tyrosine phosphorylation (i.e. aa 412-422) in the Rous sarcoma virus (RSV)-encoded transforming protein pp60v-src. This substrate sequence, RRLIEDNEYTARG, was originally described as an EGFR (epidermal growth factor receptor) substrate in A431 cell extracts (K|m|=0.3-0.6 mM).|In vitro|tyrosine phosphorylation of the peptide is stimulated by EGF (epidermal growth factor). The compound has shown an ability to reverse the kinase process much like DTT (1,4-Dithiothreitol) which has resulted in the increased activity of the insulin receptor/kinase.

Names and Identifiers

IUPAC Name 4-[[4-amino-2-[[2-[[2-[[2-[[2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-5-[[1-[[1-[[1-[[1-(carboxymethylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
INCHI InChI=1S/C66H109N23O23/c1-7-31(4)50(88-60(109)41(25-30(2)3)84-55(104)38(13-10-24-77-66(73)74)81-53(102)36(67)11-8-22-75-64(69)70)62(111)83-40(19-21-47(95)96)57(106)87-44(28-48(97)98)59(108)86-43(27-45(68)92)58(107)82-39(18-20-46(93)94)56(105)85-42(26-34-14-16-35(91)17-15-34)61(110)89-51(33(6)90)63(112)79-32(5)52(101)80-37(12-9-23-76-65(71)72)54(103)78-29-49(99)100/h14-17,30-33,36-44,50-51,90-91H,7-13,18-29,67H2,1-6H3,(H2,68,92)(H,78,103)(H,79,112)(H,80,101)(H,81,102)(H,82,107)(H,83,111)(H,84,104)(H,85,105)(H,86,108)(H,87,106)(H,88,109)(H,89,110)(H,93,94)(H,95,96)(H,97,98)(H,99,100)(H4,69,70,75)(H4,71,72,76)(H4,73,74,77)
InChi Key FCOIFWGQVMAMSM-UHFFFAOYSA-N
Canonical SMILES CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)O)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N
Isomeric SMILES CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)O)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N
WGK Germany 3
PubChem CID 25090755
Molecular Weight 1592.9

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (partly ).
Refractive Indexn20D1.66

Safety and Hazards(GHS)

WGK Germany 3

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