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PPP2R4 Antibody - Primary antibody, specific to PPP2R4, Rabbit IgG

  • Carrier Free
  • ExactAb™
  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human PPP2R4 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab122864
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab122864-10μl
10μl
In stock
$66.90
Ab122864-50μl
50μl
In stock
$189.90
Ab122864-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab122864-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,819.90

pAb; Rabbit anti Human PPP2R4 Antibody; WB, IHC; Unconjugated

Basic Description

Product NamePPP2R4 Antibody - Primary antibody, specific to PPP2R4, Rabbit IgG
Synonymssubunit B'' antibody; KIAA0044antibody; MGC2184antibody; Phosphotyrosyl phosphatase activator antibody; PP2A antibody; PP2A phosphatase activatorantibody; PP2A subunit B' antibody; PP2A subunit B' isoform PR53 antibody; PP2A subunit B' PR53 isoformantibod
Specifications & PurityExactAb™, Validated, Carrier Free, 1.0 mg/mL
Host speciesRabbit
SpecificityPPP2R4
ImmunogenA synthetic peptide derived from human PTPA (AA 347-358)
Positive ControlWB: Hep G2, HeLa, NIH/3T3 and C6 cell lysates. IHC: Human thyroid cancer tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human PPP2R4 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activty of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

PPP2R4 Antibody (Ab122864) - Western Blot
All lanes: PPP2R4 Antibody (Ab122864) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution

Predicted band size: 41 kDa
Observed band size: 43 kDa
Exposure time: 4.1 s

PPP2R4 Antibody (Ab122864) - Western Blot
All lanes: PPP2R4 Antibody (Ab122864) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution

Predicted band size: 41 kDa
Observed band size: 36, 43 kDa
Exposure time: 1.0 s

PPP2R4 Antibody (Ab122864) - IHC
Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using PPP2R4 Antibody (Ab122864). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

PTPA Tchem Serine/threonine-protein phosphatase 2A activator 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303429Certificate of AnalysisMar 20, 2024 Ab122864
ZJ24F0303430Certificate of AnalysisMar 20, 2024 Ab122864

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