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PR-619 - 10mM in DMSO, high purity , CAS No.2645-32-1
Cell-permeable, non-selective and reversible DUB inhibitor
Basic Description
Synonyms | PR-619|2645-32-1|3,5-dithiocyanatopyridine-2,6-diamine|PR 619|2,6-Diamino-3,5-dithiocyanopyridine|(2,6-diamino-5-thiocyanatopyridin-3-yl) thiocyanate|3,5-Bis-thiocyanato-pyridine-2,6-diamine|{[2,6-DIAMINO-5-(CYANOSULFANYL)PYRIDIN-3-YL]SULFANYL}FORMONITRIL |
Specifications & Purity | 10mM in DMSO |
Storage Temp | Store at -80°C |
Shipped In | Dry ice |
Product Description | PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM. |
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Names and Identifiers
IUPAC Name | (2,6-diamino-5-thiocyanatopyridin-3-yl) thiocyanate |
INCHI | InChI=1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12) |
InChi Key | ZXOBLNBVNROVLC-UHFFFAOYSA-N |
Canonical SMILES | C1=C(C(=NC(=C1SC#N)N)N)SC#N |
Isomeric SMILES | C1=C(C(=NC(=C1SC#N)N)N)SC#N |
WGK Germany | 3 |
PubChem CID | 2817763 |
Molecular Weight | 223.28 |
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Safety and Hazards(GHS)
Pictogram(s) | GHS05, GHS07 |
Signal | Danger |
Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
WGK Germany | 3 |
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