Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Prednisone acetate|Prednisone 21-acetate|125-10-0|Cortancyl|Delcortin|Deltalone|Nisone|delta-corlin|delta1-Cortisone-21-acetate|Pregna-1,4-diene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-|delta'-Dehydrocortisone acetate|prednisone-21-acetate|NSC 10965|U 6 |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Glucocorticoid. Increases apoptosis in mature activated blood lymphocytes. |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
|
Associated Targets
CBX1 Tbio Chromobox protein homolog 1 0 Activities
KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Names and Identifiers
| IUPAC Name | [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
|---|---|
| INCHI | InChI=1S/C23H28O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-17,20,28H,4-5,7,9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1 |
| InChi Key | MOVRKLZUVNCBIP-RFZYENFJSA-N |
| Canonical SMILES | CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O |
| Isomeric SMILES | CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)C)O |
| PubChem CID | 91438 |
| Molecular Weight | 400.46 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2101380 | Certificate of Analysis | Jun 20, 2024 | P302294 |
| I2101382 | Certificate of Analysis | Jun 20, 2024 | P302294 |
| I2101381 | Certificate of Analysis | Jun 12, 2024 | P302294 |
| G2415560 | Certificate of Analysis | May 21, 2024 | P302294 |
| G2415562 | Certificate of Analysis | May 21, 2024 | P302294 |
| G2415563 | Certificate of Analysis | May 21, 2024 | P302294 |
| G2415572 | Certificate of Analysis | May 21, 2024 | P302294 |
| A2429379 | Certificate of Analysis | Aug 18, 2021 | P302294 |
| E2413033 | Certificate of Analysis | Aug 18, 2021 | P302294 |
| F2307355 | Certificate of Analysis | Aug 18, 2021 | P302294 |
Chemical and Physical Properties
| Refractive Index | 1.579 |
|---|---|
| Flash Point(°C) | 200.2ºC |
| Boil Point(°C) | 582ºC |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H335:May cause respiratory irritation H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell. |