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Procaine hydrochloride - 99%, high purity , CAS No.51-05-8

  • ≥99%
Item Number
P113899
Grouped product items
SKUSizeAvailabilityPrice Qty
P113899-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
P113899-25g
25g
In stock
$33.90
P113899-100g
100g
In stock
$83.90
P113899-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$189.90

Na + channel blocker. DNA methylation inhibitor.

View related series
Benzene compounds

Basic Description

SynonymsPROCAINE HYDROCHLORIDE|51-05-8|Procaine Hcl|Naucaine|Neocaine|Omnicain|Planocaine|Anestil|Novocain|2-(diethylamino)ethyl 4-aminobenzoate hydrochloride|Atoxicocaine|Neotonocaine|Allocaine|Aminocaine|Anadolor|Anesthesol|Bernocaine|Chlorocaine|Ethocaine|Euge
Specifications & Purity≥99%
Biochemical and Physiological MechanismsProcaine is a Na+ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine.It is also useful as a painkiller to treat pain, associated with joints and tendons
Storage TempArgon charged
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.
A sodium channel blocker and DNA methylation inhibitor

Application:

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSF1 Tchem Heat shock factor protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BLM Tchem Bloom syndrome protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TARDBP Tchem TAR DNA-binding protein 43 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NPSR1 Tchem Neuropeptide S receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488179937
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179937
IUPAC Name 2-(diethylamino)ethyl 4-aminobenzoate;hydrochloride
INCHI InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
InChi Key HCBIBCJNVBAKAB-UHFFFAOYSA-N
Canonical SMILES CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
Isomeric SMILES CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
WGK Germany 3
RTECS DG2275000
PubChem CID 5795
UN Number 2811
Molecular Weight 272.77
Beilstein 3917802

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot NumberCertificate TypeDateItem
G2418414Certificate of AnalysisJul 09, 2024 P113899
G2418415Certificate of AnalysisJul 09, 2024 P113899
G2418433Certificate of AnalysisJul 09, 2024 P113899
G2418434Certificate of AnalysisJul 09, 2024 P113899
G2418450Certificate of AnalysisJul 09, 2024 P113899
B2310333Certificate of AnalysisDec 16, 2021 P113899
C2425075Certificate of AnalysisDec 16, 2021 P113899
F2307350Certificate of AnalysisDec 16, 2021 P113899
J2331112Certificate of AnalysisDec 16, 2021 P113899
E2128504Certificate of AnalysisJun 07, 2021 P113899
B2310334Certificate of AnalysisApr 09, 2021 P113899
D2324753Certificate of AnalysisApr 09, 2021 P113899

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Chemical and Physical Properties

SolubilitySoluble in ethanol, slightly soluble in chloroform, insoluble in ether
SensitivityLight and Air sensitive
Melt Point(°C)155-156°C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H317:May cause an allergic skin reaction

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/...

WGK Germany 3
RTECS DG2275000
Merck Index 7757

Related Documents

Solution Calculators