Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P113899-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
P113899-25g | 25g | In stock | $33.90 | |
P113899-100g | 100g | In stock | $83.90 | |
P113899-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $189.90 |
Na + channel blocker. DNA methylation inhibitor.
Synonyms | PROCAINE HYDROCHLORIDE|51-05-8|Procaine Hcl|Naucaine|Neocaine|Omnicain|Planocaine|Anestil|Novocain|2-(diethylamino)ethyl 4-aminobenzoate hydrochloride|Atoxicocaine|Neotonocaine|Allocaine|Aminocaine|Anadolor|Anesthesol|Bernocaine|Chlorocaine|Ethocaine|Euge |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Procaine is a Na+ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine.It is also useful as a painkiller to treat pain, associated with joints and tendons |
Storage Temp | Argon charged |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM. Application: Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay. |
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Pubchem Sid | 488179937 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179937 |
IUPAC Name | 2-(diethylamino)ethyl 4-aminobenzoate;hydrochloride |
INCHI | InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H |
InChi Key | HCBIBCJNVBAKAB-UHFFFAOYSA-N |
Canonical SMILES | CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl |
Isomeric SMILES | CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl |
WGK Germany | 3 |
RTECS | DG2275000 |
PubChem CID | 5795 |
UN Number | 2811 |
Molecular Weight | 272.77 |
Beilstein | 3917802 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2418414 | Certificate of Analysis | Jul 09, 2024 | P113899 |
G2418415 | Certificate of Analysis | Jul 09, 2024 | P113899 |
G2418433 | Certificate of Analysis | Jul 09, 2024 | P113899 |
G2418434 | Certificate of Analysis | Jul 09, 2024 | P113899 |
G2418450 | Certificate of Analysis | Jul 09, 2024 | P113899 |
B2310333 | Certificate of Analysis | Dec 16, 2021 | P113899 |
C2425075 | Certificate of Analysis | Dec 16, 2021 | P113899 |
F2307350 | Certificate of Analysis | Dec 16, 2021 | P113899 |
J2331112 | Certificate of Analysis | Dec 16, 2021 | P113899 |
E2128504 | Certificate of Analysis | Jun 07, 2021 | P113899 |
B2310334 | Certificate of Analysis | Apr 09, 2021 | P113899 |
D2324753 | Certificate of Analysis | Apr 09, 2021 | P113899 |
Solubility | Soluble in ethanol, slightly soluble in chloroform, insoluble in ether |
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Sensitivity | Light and Air sensitive |
Melt Point(°C) | 155-156°C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H317:May cause an allergic skin reaction |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... |
WGK Germany | 3 |
RTECS | DG2275000 |
Merck Index | 7757 |
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