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Procarbazine HCl - ≥98%, high purity , DNA inhibitor, CAS No.366-70-1, DNA inhibitor

  • ≥98%
Item Number
P129854
Grouped product items
SKUSizeAvailabilityPrice Qty
P129854-50mg
50mg
In stock
$25.90
P129854-250mg
250mg
In stock
$97.90
P129854-1g
1g
In stock
$299.90
P129854-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,346.90

Clastogen and genotoxic carcinogen

Basic Description

SynonymsProcarbazine hydrochloride|366-70-1|PROCARBAZINE HCl|Matulane|Nathulane|Natunalar|MIH hydrochloride|PCB hydrochloride|Ibenzmethyzine hydrochloride|Natulan|Procarbazine.HCl|Natulan hydrochloride|NSC-77213|Procarbazine (Hydrochloride)|Procarbazine chloridra
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPrimaquine phosphate is an antineoplastic agent.Clastogen and genotoxic carcinogen. Induces chromosomal damage and mutations. Antineoplastic agent. Active in vivo and in vitro.
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionDNA inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Procarbazine HCl is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.
An antineoplastic agent.

Associated Targets

CBX1 Tbio Chromobox protein homolog 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC3 Tbio Canalicular multispecific organic anion transporter 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC4 Tchem Multidrug resistance-associated protein 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCB11 Tchem Bile salt export pump 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488181015
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181015
IUPAC Name 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride
INCHI InChI=1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
InChi Key DERJYEZSLHIUKF-UHFFFAOYSA-N
Canonical SMILES CC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl
Isomeric SMILES CC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl
WGK Germany 3
PubChem CID 9703
Molecular Weight 257.76

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
D23211567Certificate of AnalysisMar 16, 2023 P129854
D23211584Certificate of AnalysisMar 16, 2023 P129854
D23211585Certificate of AnalysisMar 16, 2023 P129854
D23211656Certificate of AnalysisMar 16, 2023 P129854
F1509100Certificate of AnalysisJan 25, 2023 P129854

Chemical and Physical Properties

SolubilitySoluble in water (52 mg/ml at 25 °C), DMSO (≥18 mg/ml), methanol, and ethanol (52 mg/ml at 25 °C).
Melt Point(°C)226 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H341:Suspected of causing genetic defects

H302:Harmful if swallowed

H360:May damage fertility or the unborn child

H350:May cause cancer

Precautionary Statements

P201:Obtain special instructions before use.

P308+P313:IF exposed or concerned: Get medical advice/attention.

P281:Use personal protective equipment as required.

WGK Germany 3
Merck Index 7758

Related Documents

Solution Calculators