ProClin preservatives are water-soluble formulations of biocides that are among the most effective biocides in the IVD industry, used in over 1,000 FDA registered IVD kits from industry-leading diagnostic manufacturers. At low working concentrations, ProClin products help extend the shelf life of IVD reagents by effectively and immediately inhibiting a broad spectrum of microbes.
ProClin biocides attack the Krebs cycle at four key points: the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. Because all bacteria and fungi possess at least part of the Krebs cycle, they are broad spectrum in their activity.
Unlike other biocides, ProClin preservatives present reduced health hazards, toxicology problems, and disposal issues at recommended usage levels.
We offer four unique formulations, ensuring a variety of options to meet a wide range of specific needs.
Product Application:
ProClin biocides are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high levels of resistance, making ProClin highly efficient even over extended storage periods of your IVD components.
Product Name
ProClin™ 150
ProClin™ 200
ProClin™ 300
ProClin™ 950
Active Ingredient(A.I.) %
CMIT/MIT(1.5)
CMIT/MIT(1.5)
CMIT/MIT(3)
MIT(9.5)
Stabilizer
23-25% Mg salts
3% Mg and Cu salts
Alkyl Carboxylate (salt-free)
None
Matrix
Water
Water
Modified glycol
Water
Working pH Range
2.5 - 8.5
2.5 - 8.5
2.5 - 8.5
2-12
Temperature Range
< 45 °C
< 45 °C
< 45 °C
< 90 °C
Typical Dosage Levels(W/W)
0.06 - 0.10%(9 – 15 ppm A.I.)
0.06 - 0.10%(9 – 15 ppm A.I.)
0.03 - 0.05%(9 – 15 ppm A.I.)
0.05 - 0.10%(50 – 150 ppm A.I.)
Shelf Life
2 years
18 months
3 years
3 years
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.