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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P287748-50mg | 50mg | In stock | $58.90 | |
P287748-100mg | 100mg | In stock | $107.90 | |
P287748-500mg | 500mg | In stock | $486.90 |
Non-selective CCK antagonist
Synonyms | Proglumide sodium salt|99247-33-3|Proglumide sodium|Proglumide (sodium)|MLS000069382|sodium;4-benzamido-5-(dipropylamino)-5-oxopentanoate|SMR000058765|4-(Benzoylamino)-5-(dipropylamino)-5-oxopentanoicacidsodiumsalt|sodium 4-benzamido-5-(dipropylamino)-5-o |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Non-selective cholecystokinin (CCK) antagonist. Inhibits CCK-stimulated amylase secretion and prevents CCK-induced 2-deoxyglucose uptake in mouse pancreatic acini. Blocks growth of HT29 colon carcinoma cells in response to gastrin 17 treatment. Orally act |
Storage Temp | Store at 2-8°C,Argon charged,Desiccated |
Shipped In | Wet ice |
Product Description | Application: Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | sodium;4-benzamido-5-(dipropylamino)-5-oxopentanoate |
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INCHI | InChI=1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1 |
InChi Key | UFMWGCINVOIJSO-UHFFFAOYSA-M |
Canonical SMILES | CCCN(CCC)C(=O)C(CCC(=O)[O-])NC(=O)C1=CC=CC=C1.[Na+] |
Isomeric SMILES | CCCN(CCC)C(=O)C(CCC(=O)[O-])NC(=O)C1=CC=CC=C1.[Na+] |
Alternate CAS | 6620-60-6 |
PubChem CID | 23677833 |
Molecular Weight | 356.39 |
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Lot Number | Certificate Type | Date | Item |
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L22081031 | Certificate of Analysis | Oct 24, 2022 | P287748 |
L22081037 | Certificate of Analysis | Oct 24, 2022 | P287748 |
L22081038 | Certificate of Analysis | Oct 24, 2022 | P287748 |
Solubility | Solvent:water, Max Conc. mg/mL: 35.64, Max Conc. mM: 100 |
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