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Propranolol hydrochloride - ≥99%, high purity , Beta-2 adrenergic receptor antagonist, CAS No.318-98-9, Beta-2 adrenergic receptor antagonist
Potent β adrenoceptor antagonist
Basic Description Synonyms Propranolol hydrochloride|318-98-9|Propranolol Hcl|Inderal|Avlocardyl|Caridolol|Inderalici|Dociton|3506-09-0|Anaprilin|Apsolol|Beprane|Berkolol|Deralin|Herzbase|Indobloc|Naprilin|Pronovan|Pylapron|Sloprolol|Ikopal|Tesnol|Kemi|Beta Neg|InnoPran XL|Proprano Specifications & Purity ≥99% Biochemical and Physiological Mechanisms Potent, non-selective β adrenoceptor antagonist. Blood-brain barrier penetrant. Storage Temp Store at -20°C,Argon charged,Desiccated Shipped In Ice chest + Ice pads Action Type ANTAGONIST Mechanism of action Beta-2 adrenergic receptor antagonist Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Names and Identifiers Pubchem Sid 488183616 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183616 IUPAC Name 1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride INCHI InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H InChi Key ZMRUPTIKESYGQW-UHFFFAOYSA-N Canonical SMILES CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl Isomeric SMILES CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl Alternate CAS 3506-09-0 PubChem CID 62882 Molecular Weight 295.81
Chemical and Physical Properties Solubility Soluble in water to 100 mM Sensitivity Moisture sensitive Melt Point(°C) 163-165°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H317: May cause an allergic skin reaction
H312: Harmful in contact with skin
H332: Harmful if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
P317: Get emergency medical help.
References 1. Jiang W et al.. (2017) Spleen contributes to restraint stress induced changes in blood leukocytes distribution.. Sci Rep, 7 (6501). [PMID:28747688 ]
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