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Prostaglandin D2 - ≥99%, high purity , CAS No.41598-07-6, Agonist of DP 1 receptor;Agonist of DP 2 receptor;Agonist of EP 1 receptor;Agonist of EP 2 receptor;Agonist of EP 3 receptor;Agonist of EP 4 receptor;Agonist of FP receptor

  • Moligand™
  • ≥99%
Item Number
P275206
Grouped product items
SKUSizeAvailabilityPrice Qty
P275206-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$189.90
P275206-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$659.90

High affinity DP 1 and CRTH2 receptor agonist. Major prostaglandin produced by mast cells.

Basic Description

Synonymsprostaglandin D2|PGD2|41598-07-6|11-Dehydroprostaglandin F2-alpha|11-Dehydroprostaglandin F2alpha|BRN 2170623|(5Z,13E,15S)-9alpha,15-Dihydroxy-11-oxoprosta-5,13-dienoate|RXY07S6CZ2|(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopenty
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsThe main prostaglandins in brain; Induce inflammation; Stimulation of adenylate cyclase.
Storage TempStore at -20°C,Argon charged,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of DP 1 receptor;Agonist of DP 2 receptor;Agonist of EP 1 receptor;Agonist of EP 2 receptor;Agonist of EP 3 receptor;Agonist of EP 4 receptor;Agonist of FP receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Product Describtion:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.


Product Application:

Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.

Associated Targets

SLCO2A1 Tchem Solute carrier organic anion transporter family member 2A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO3A1 Tbio Solute carrier organic anion transporter family member 3A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER2 Tclin Prostaglandin E2 receptor EP2 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGDR Tclin Prostaglandin D2 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER4 Tclin Prostaglandin E2 receptor EP4 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGDR2 Tchem Prostaglandin D2 receptor 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER1 Tclin Prostaglandin E2 receptor EP1 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGFR Tclin Prostaglandin F2-alpha receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER3 Tclin Prostaglandin E2 receptor EP3 subtype 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARA Tclin Peroxisome proliferator-activated receptor alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid
INCHI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
InChi Key BHMBVRSPMRCCGG-OUTUXVNYSA-N
Canonical SMILES CCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)O)O
Isomeric SMILES CCCCC[C@@H](/C=C/[C@@H]1[C@H]([C@H](CC1=O)O)C/C=C\CCCC(=O)O)O
Alternate CAS 41598-07-6
PubChem CID 448457
MeSH Entry Terms 11 Dehydroprostaglandin F2 alpha;11 Dehydroprostaglandin F2alpha;11-Dehydroprostaglandin F2 alpha;11-Dehydroprostaglandin F2alpha;alpha, 11-Dehydroprostaglandin F2;D2, Prostaglandin;F2 alpha, 11-Dehydroprostaglandin;F2alpha, 11-Dehydroprostaglandin;PGD2;P
Molecular Weight 352.47

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

7 results found

Lot NumberCertificate TypeDateItem
C2426322Certificate of AnalysisMar 14, 2024 P275206
C2426323Certificate of AnalysisMar 14, 2024 P275206
G2401030Certificate of AnalysisMar 14, 2024 P275206
C2325804Certificate of AnalysisJan 12, 2024 P275206
C2325825Certificate of AnalysisJan 12, 2024 P275206
F2229558Certificate of AnalysisJun 16, 2022 P275206
F2229560Certificate of AnalysisJun 16, 2022 P275206

Chemical and Physical Properties

SolubilityChloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly)
SensitivityLight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H360:May damage fertility or the unborn child

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

Related Documents

Solution Calculators