Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P275206-1mg | 1mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $189.90 | |
P275206-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $659.90 |
High affinity DP 1 and CRTH2 receptor agonist. Major prostaglandin produced by mast cells.
Synonyms | prostaglandin D2|PGD2|41598-07-6|11-Dehydroprostaglandin F2-alpha|11-Dehydroprostaglandin F2alpha|BRN 2170623|(5Z,13E,15S)-9alpha,15-Dihydroxy-11-oxoprosta-5,13-dienoate|RXY07S6CZ2|(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopenty |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | The main prostaglandins in brain; Induce inflammation; Stimulation of adenylate cyclase. |
Storage Temp | Store at -20°C,Argon charged,Desiccated |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of DP 1 receptor;Agonist of DP 2 receptor;Agonist of EP 1 receptor;Agonist of EP 2 receptor;Agonist of EP 3 receptor;Agonist of EP 4 receptor;Agonist of FP receptor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Product Describtion: Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. Product Application: Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma. |
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IUPAC Name | (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid |
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INCHI | InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1 |
InChi Key | BHMBVRSPMRCCGG-OUTUXVNYSA-N |
Canonical SMILES | CCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)O)O |
Isomeric SMILES | CCCCC[C@@H](/C=C/[C@@H]1[C@H]([C@H](CC1=O)O)C/C=C\CCCC(=O)O)O |
Alternate CAS | 41598-07-6 |
PubChem CID | 448457 |
MeSH Entry Terms | 11 Dehydroprostaglandin F2 alpha;11 Dehydroprostaglandin F2alpha;11-Dehydroprostaglandin F2 alpha;11-Dehydroprostaglandin F2alpha;alpha, 11-Dehydroprostaglandin F2;D2, Prostaglandin;F2 alpha, 11-Dehydroprostaglandin;F2alpha, 11-Dehydroprostaglandin;PGD2;P |
Molecular Weight | 352.47 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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C2426322 | Certificate of Analysis | Mar 14, 2024 | P275206 |
C2426323 | Certificate of Analysis | Mar 14, 2024 | P275206 |
G2401030 | Certificate of Analysis | Mar 14, 2024 | P275206 |
C2325804 | Certificate of Analysis | Jan 12, 2024 | P275206 |
C2325825 | Certificate of Analysis | Jan 12, 2024 | P275206 |
F2229558 | Certificate of Analysis | Jun 16, 2022 | P275206 |
F2229560 | Certificate of Analysis | Jun 16, 2022 | P275206 |
Solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly) |
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Sensitivity | Light sensitive |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H360:May damage fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |