Prostaglandin E₃ - A solution in methyl acetate, high purity , CAS No.802-31-3

Item Number

P355929

Grouped product items
SKU	Size	Availability	Price	Qty
P355929-50μg	50μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$559.90
P355929-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90

a metabolite found in ocular tissue

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Basic Description

Synonyms	prostaglandin E3 \| PGE3 \| 802-31-3 \| ZED6SBL53S \| 9-oxo-11R,15S-dihydroxy-5Z,13E,17Z-prostatrienoic acid \| CHEBI:28031 \| (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid \| Prosta-5,13,17-trien-1-oicacid, 11,15-dihyd
Specifications & Purity	≥98%, 500 ug/mL in methyl acetate
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Prostaglandin E3 is formed via the COX metabolism of eicosapentaenoic acid, where in human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 μg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.

Names and Identifiers

IUPAC Name	(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid
INCHI	InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
InChi Key	CBOMORHDRONZRN-QLOYDKTKSA-N
Canonical SMILES	O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C/C=C\CC)[C@H](O)C1
Isomeric SMILES	CC/C=C\C[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O
PubChem CID	5280937
Molecular Weight	350.45
Beilstein	2899956

Solubility

Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), DMF (~100 mg/ml), PBS (pH7.2) (~5 mg/ml), and water (>5 mg/ml at 25° C).

Refractive Index

n20D1.58 (Predicted)

Boil Point(°C)

57° C

Melt Point(°C)

-98.05° C

Solution Calculators

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Basic Description