| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P755675-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $301.90 |
| Specifications & Purity | γ-irradiated, BioReagent, for cell culture, powder |
|---|---|
| Biochemical and Physiological Mechanisms | Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Grade | BioReagent, for cell culture, γ-irradiated |
| Product Description | For use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation. Prostaglandin E2 has been used to determine its effects on collagen gel contraction mediated by alveolar cell carcinoma cell line A549. |
| ALogP | 2.8 |
|---|
| IUPAC Name | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid |
|---|---|
| INCHI | InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 |
| InChi Key | XEYBRNLFEZDVAW-ARSRFYASSA-N |
| Canonical SMILES | CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O |
| Isomeric SMILES | CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O |
| RTECS | UK8000000 |
| PubChem CID | 5280360 |
| Molecular Weight | 352.47 |
| Reaxy-Rn | 2224724 |
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| Solubility | ethanol: 1 mg/mL |
|---|---|
| Melt Point(°C) | 66°C(lit.) |
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H302:Harmful if swallowed H360:May damage fertility or the unborn child |
| Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |
| RTECS | UK8000000 |
| Reaxy-Rn | 2224724 |
| Merck Index | 7877 |
