JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

PROTAC BRD4 Degrader-12 - 99%, high purity , CAS No.2417370-90-0

Item Number

P647304

Grouped product items
SKU	Size	Availability	Price	Qty
P647304-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$360.90
P647304-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,000.90

View related series

Basic Description

Specifications & Purity	99%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC 50 of 0.39 nM and 0.24 nM, respectively. Form:Solid

Canonical SMILES	CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@H](CN3C([C@@H](NC(CCCCCCCCCCNC(C4=CC(N(C5=NC=C(F)C=C5F)CC6=CNC7=C6C8=CN(C)C7=O)=C8C=C4CS(=O)(C)=O)=O)=O)C(C)(C)C)=O)OC(OC(C)C(C)SS(C)(=O)=O)=O)=O)C=C2
Molecular Weight	1306.58

Enter Lot Number to search for COA:

Solubility	DMSO : 100 mg/mL (76.54 mM; Need ultrasonic)

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.