Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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H330535-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $147.90 | |
H330535-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
H330535-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $189.90 | |
H330535-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 |
an inhibitor of PKA and PKC
Synonyms | HMS2231B22 | 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline | MLS000069615 | SCHEMBL190590 | cid_3542 | CS-0142529 | NCGC00015487-09 | BRD6846 | BRD-6846 | NCGC00015487-12 | 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE | H-7 inhibitor | DB07996 | HY-1319 |
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Specifications & Purity | ≥98% |
Storage Temp | Store at 2-8°C,Protected from light |
Shipped In | Wet ice |
Product Description | H-7 is an inhibitor of the cyclic nucleotide dependent protein kinases PKA and PKC. Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC. |
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IUPAC Name | 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline |
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INCHI | InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3 |
InChi Key | BDVFVCGFMNCYPV-UHFFFAOYSA-N |
Canonical SMILES | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
Isomeric SMILES | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
WGK Germany | 3 |
RTECS | TL9305000 |
PubChem CID | 3542 |
Molecular Weight | 291.37 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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B2426836 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426837 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426842 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426845 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426847 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426848 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426849 | Certificate of Analysis | Jan 19, 2024 | H330535 |
B2426850 | Certificate of Analysis | Jan 19, 2024 | H330535 |
Solubility | Soluble in Ethanol: 20 mg/mL and 1 M HCl: 5 mg/mL |
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Sensitivity | light sensitive |
Boil Point(°C) | ~495.3° C at 760 mmHg (Predicted) |
Melt Point(°C) | 114° C |
WGK Germany | 3 |
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RTECS | TL9305000 |
RIDADR | NONHforallmodesoftransport |