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Protriptyline Hydrochloride - ≥98%, high purity , CAS No.1225-55-4, Norepinephrine transporter inhibitor

≥98%

CAS#: 1225-55-4
Formula: C₁₉H₂₂ClN
Molecular Weight: 299.838
MDL number: MFCD00072057
PubChem CID: 6603149

Item Number

P137447

Grouped product items
SKU	Size	Availability	Price	Qty
P137447-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$109.90
P137447-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90

View related series

Cholinesterase (ChE) G protein signal

Basic Description

Synonyms	Protriptyline hydrochloride\|1225-55-4\|Protriptyline HCl\|Concordin\|Maximed\|Triptyl\|Protriptyline (hydrochloride)\|Triptil hydrochloride\|Normethyl EX4442\|MK-240\|NSC-169912\|DTXSID8046951\|UNII-44665V00O8\|EINECS 214-956-3\|NSC 169912\|5H-Dibenzo[a,d]cycloheptene-
Specifications & Purity	≥98%
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Norepinephrine transporter inhibitor
Product Description	Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

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FTL Tbio Ferritin light chain 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMN1 Tchem Survival motor neuron protein 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IMPA1 Tclin Inositol monophosphatase 1 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Discover Target: KDM4E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyl)propan-1-amine;hydrochloride
INCHI	InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H
InChi Key	OGQDIIKRQRZXJH-UHFFFAOYSA-N
Canonical SMILES	CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl
Isomeric SMILES	CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl
WGK Germany	3
RTECS	HP1400000
PubChem CID	6603149
Molecular Weight	299.838

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
G2429512	Certificate of Analysis	Aug 05, 2024	P137447
G2429513	Certificate of Analysis	Aug 05, 2024	P137447
G2429514	Certificate of Analysis	Aug 05, 2024	P137447
G2429515	Certificate of Analysis	Aug 05, 2024	P137447

Solubility

solubility H2O: 50 mg/mL;

Sensitivity

Light sensitive；Moisture sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	HP1400000

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