Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Protriptyline hydrochloride|1225-55-4|Protriptyline HCl|Concordin|Maximed|Triptyl|Protriptyline (hydrochloride)|Triptil hydrochloride|Normethyl EX4442|MK-240|NSC-169912|DTXSID8046951|UNII-44665V00O8|EINECS 214-956-3|NSC 169912|5H-Dibenzo[a,d]cycloheptene- |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | A norepinephrine uptake blocker. |
Associated Targets
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities
GMNN Tbio Geminin 0 Activities
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FTL Tbio Ferritin light chain 0 Activities
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KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities
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SMN1 Tchem Survival motor neuron protein 0 Activities
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PMP22 Tbio Peripheral myelin protein 22 0 Activities
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
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IMPA1 Tclin Inositol monophosphatase 1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KDM4E Tchem Lysine-specific demethylase 4E 0 Activities
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Names and Identifiers
| IUPAC Name | N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyl)propan-1-amine;hydrochloride |
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| INCHI | InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H |
| InChi Key | OGQDIIKRQRZXJH-UHFFFAOYSA-N |
| Canonical SMILES | CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl |
| Isomeric SMILES | CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl |
| WGK Germany | 3 |
| RTECS | HP1400000 |
| PubChem CID | 6603149 |
| Molecular Weight | 299.838 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | Light sensitive |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | HP1400000 |