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PSB 1114 - ≥98%(HPLC), high purity , CAS No.1657025-60-9, Agonist of P2Y 2 receptor

  • Moligand™
  • ≥98%(HPLC)
Item Number
P288132
Grouped product items
SKUSizeAvailabilityPrice Qty
P288132-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$324.90

Potent, selective P2Y2agonist

View related series
P2Y2 receptor Agonist

Basic Description

Synonyms4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsPotent, selective P2Y2agonist (EC50= 0.134μM). Displays >60-fold selectivity versus P2Y4and P2Y6receptors.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of P2Y 2 receptor

Associated Targets

P2RY2 Tclin P2Y purinoceptor 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RY6 Tchem P2Y purinoceptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RY4 Tchem P2Y purinoceptor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]-difluoromethyl]phosphonic acid
INCHI InChI=1S/C10H15F2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(15)7(16)8(26-4)14-2-1-5(31)13-9(14)17/h1-2,4,6-8,15-16H,3H2,(H,21,22)(H,23,24)(H,13,17,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1
InChi Key DFGBPSGNGNHNQM-XVFCMESISA-N
Canonical SMILES C1=CN(C(=O)NC1=S)C2C(C(C(O2)COP(=O)(O)OP(=O)(C(F)(F)P(=O)(O)O)O)O)O
Isomeric SMILES C1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(C(F)(F)P(=O)(O)O)O)O)O
PubChem CID 52952605
Molecular Weight 622.14

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (supplied pre-dissolved at a concentration of 10mM)

Related Documents

Solution Calculators