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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P647021-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $145.90 | |
P647021-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $420.90 | |
P647021-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $620.90 |
Ketones, Aldehydes, Acids
Synonyms | Pterosin B|34175-96-7|(2R)-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydroinden-1-one|BI 2|PterosinB|(R)-6-(2-Hydroxyethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one|1-Indanone, 6-(2-hydroxyethyl)-2,5,7-trimethyl-, (-)-|1H-Inden-1-one, 2,3-dihydro-6-(2-hy |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Pterosin B, a indanone found in bracken fern ( Pteridium aquilinum ), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Pterosin B, a indanone found in bracken fern ( Pteridium aquilinum ), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Form:Solid |
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IUPAC Name | (2R)-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydroinden-1-one |
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INCHI | InChI=1S/C14H18O2/c1-8-6-11-7-9(2)14(16)13(11)10(3)12(8)4-5-15/h6,9,15H,4-5,7H2,1-3H3/t9-/m1/s1 |
InChi Key | SJNCSXMTBXDZQA-SECBINFHSA-N |
Canonical SMILES | CC1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C |
Isomeric SMILES | C[C@@H]1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C |
Alternate CAS | 34175-96-7 |
PubChem CID | 115049 |
MeSH Entry Terms | pterosin B |
Molecular Weight | 218.29 |
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Solubility | DMSO : 250 mg/mL (1145.27 mM; Need ultrasonic) |
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