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Pterosin B - 99%, high purity , CAS No.34175-96-7

  • ≥99%
Item Number
P647021
Grouped product items
SKUSizeAvailabilityPrice Qty
P647021-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$145.90
P647021-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
P647021-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$620.90

Ketones, Aldehydes, Acids

Basic Description

SynonymsPterosin B|34175-96-7|(2R)-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydroinden-1-one|BI 2|PterosinB|(R)-6-(2-Hydroxyethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one|1-Indanone, 6-(2-hydroxyethyl)-2,5,7-trimethyl-, (-)-|1H-Inden-1-one, 2,3-dihydro-6-(2-hy
Specifications & Purity≥99%
Biochemical and Physiological MechanismsPterosin B, a indanone found in bracken fern ( Pteridium aquilinum ), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Pterosin B, a indanone found in bracken fern ( Pteridium aquilinum ), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

Form:Solid

Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R)-6-(2-hydroxyethyl)-2,5,7-trimethyl-2,3-dihydroinden-1-one
INCHI InChI=1S/C14H18O2/c1-8-6-11-7-9(2)14(16)13(11)10(3)12(8)4-5-15/h6,9,15H,4-5,7H2,1-3H3/t9-/m1/s1
InChi Key SJNCSXMTBXDZQA-SECBINFHSA-N
Canonical SMILES CC1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C
Isomeric SMILES C[C@@H]1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C
Alternate CAS 34175-96-7
PubChem CID 115049
MeSH Entry Terms pterosin B
Molecular Weight 218.29

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 250 mg/mL (1145.27 mM; Need ultrasonic)

Related Documents

Solution Calculators