Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P111269-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $31.90 | |
P111269-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $138.90 | |
P111269-500mg | 500mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $581.90 |
Plant derived isoflavone
Synonyms | Puerarin|3681-99-0|Kakonein|Daidzein-8-C-glucoside|7-hydroxy-3-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one|Puerarin 80 mm|CHEBI:8633|Daidzein 8-c-glucoside|NPI 031G|7-hydroxy-3-(4-hydr |
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Specifications & Purity | Moligand™, analytical standard, ≥98% |
Biochemical and Physiological Mechanisms | Plant derived isoflavone. Various pharmacological functions including antioxidant, anti-inflammatory and antiapoptotic. Enhances superoxide dismutase activity. Neuroprotective and anti-ischaemic effects in vivo. Orally active |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Grade | analytical standard, Moligand™ |
Action Type | ACTIVATOR |
Mechanism of action | Activator of TRPV4 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |
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INCHI | InChI=1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1 |
InChi Key | HKEAFJYKMMKDOR-VPRICQMDSA-N |
Canonical SMILES | C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O |
Isomeric SMILES | C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O |
WGK Germany | 3 |
RTECS | UO5216000 |
Alternate CAS | 3681-99-0 |
PubChem CID | 5281807 |
MeSH Entry Terms | 7,4'-dihydroxyisoflavone-8beta-glucopyranoside;kakonein;puerarin |
Molecular Weight | 416.38 |
Beilstein | 64198 |
Reaxy-Rn | 64198 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2231769 | Certificate of Analysis | Jun 19, 2024 | P111269 |
D2423014 | Certificate of Analysis | Apr 30, 2024 | P111269 |
D2423031 | Certificate of Analysis | Apr 30, 2024 | P111269 |
G2314128 | Certificate of Analysis | Aug 17, 2022 | P111269 |
H2231612 | Certificate of Analysis | Aug 17, 2022 | P111269 |
H2231764 | Certificate of Analysis | Aug 17, 2022 | P111269 |
L2308013 | Certificate of Analysis | Aug 17, 2022 | P111269 |
Sensitivity | air & heat & Moisture sensitive |
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Melt Point(°C) | 187-189°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UO5216000 |
Reaxy-Rn | 64198 |
1. Huang SR et al.. (2020) Puerarin alleviates the progression of non-small cell lung cancer by regulating the miR-342/CCND1 axis.. Neoplasma, 67 (6): (1244-1255). [PMID:32749850] |
2. Wen S et al.. (2021) Puerarin Attenuates Cadmium-Induced Neuronal Injury via Stimulating Cadmium Excretion, Inhibiting Oxidative Stress and Apoptosis.. Biomolecules, 11 (7): [PMID:34356602] |