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pyrazolone, 1 , CAS No.P613024, Agonist of FPR1;Agonist of FPR2/ALX

Moligand™

PubChem CID: 24776341

Item Number

P613024

Grouped product items
SKU	Size	Availability	Price	Qty
P613024-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
P613024-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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FPR1 Agonist FPR2/ALX Agonist

Basic Description

Synonyms	903895-98-7\|Pyrazolone, 1\|1-(4-Chlorophenyl)-3-(5-isopropyl-1-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea\|3-(4-chlorophenyl)-1-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea\|FPR Agonist 43\|TC-FPR 43\|CHEMBL379761\|T77D5438IM\|1-(4-chlorop
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of FPR1;Agonist of FPR2/ALX

Associated Targets

FPR1 Tchem fMet-Leu-Phe receptor 1 Activities

Discover Target: FPR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR2 Tchem N-formyl peptide receptor 2 2 Activities

Discover Target: FPR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-(4-chlorophenyl)-1-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea
INCHI	InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)
InChi Key	PAEBEUZTAPIOIO-UHFFFAOYSA-N
Canonical SMILES	O=C(Nc1c(C(C)C)n(n(c1=O)c1ccccc1)C)Nc1ccc(cc1)Cl
Isomeric SMILES	CC(C)C1=C(C(=O)N(N1C)C2=CC=CC=C2)NC(=O)NC3=CC=C(C=C3)Cl
PubChem CID	24776341

ChEMBL Ligand

PubChem CID

RCSB PDB Ligand

GPCRdb Ligand

References

1. Bürli RW, Xu H, Zou X, Muller K, Golden J, Frohn M, Adlam M, Plant MH, Wong M, McElvain M et al.. (2006) Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents.. Bioorg Med Chem Lett, 16 (14): (3713-8). [PMID:16697190]
2. He HQ, Liao D, Wang ZG, Wang ZL, Zhou HC, Wang MW, Ye RD. (2013) Functional characterization of three mouse formyl peptide receptors.. Mol Pharmacol, 83 (2): (389-98). [PMID:23160941]

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pyrazolone, 1 , CAS No.P613024, Agonist of FPR1;Agonist of FPR2/ALX

Basic Description

Associated Targets

FPR1 Tchem fMet-Leu-Phe receptor 1 Activities

FPR2 Tchem N-formyl peptide receptor 2 2 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

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