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Pyridoxal 5-Phosphate Monohydrate - 10mM in DMSO, high purity , CAS No.41468-25-1
Basic Description Synonyms 41468-25-1 | Pyridoxal 5'-phosphate monohydrate | Pyridoxal 5-phosphate monohydrate | Pyridoxal phosphate hydrate | (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate | Pyridoxal phosphate monohydrate | Pyridoxal-5-phosphate Monohydrate | PYRI Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Vitamin B6 metabolite that acts as a coenzyme in transamination reactions by forming a Schiff-base linkage with lysine groups on aminotransferase. Also serves as a coenzyme in some decarboxylation and deamination reactions. Can modify lysyl and valyl resi Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate;hydrate INCHI InChI=1S/C8H10NO6P.H2O/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;/h2-3,11H,4H2,1H3,(H2,12,13,14);1H2 InChi Key CEEQUQSGVRRXQI-UHFFFAOYSA-N Canonical SMILES CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O Isomeric SMILES CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O WGK Germany 2 RTECS UV1208000 PubChem CID 38882 Molecular Weight 265.16 Beilstein 234749 Reaxy-Rn 234749
Chemical and Physical Properties Sensitivity Light & Air Sensitive. Melt Point(°C) 143 °C
Safety and Hazards(GHS) WGK Germany 2 RTECS UV1208000 Reaxy-Rn 234749 Merck Index 7979
Citations of This Product 1. Liu Jianming, Zhang Han, Xu Yingying, Meng Hao, Zeng An-Ping. (2023) Turn air-captured CO2 with methanol into amino acid and pyruvate in an ATP/NAD(P)H-free chemoenzymatic system. Nature Communications, 14 (1): (1-12). [PMID:37188719 ] [10.1038/s41467-023-38490-w ] 2. Junli Guo, Lingling Yang, Huijie Xu, Chenxi Zhao, Zhenqing Dai, Zhida Gao, Yanyan Song. (2019) Biomineralization-Driven Ion Gate in TiO2 Nanochannel Arrays for Cell H2S Sensing. ANALYTICAL CHEMISTRY, 91 (21): (13746–13751). [PMID:31559823 ] [10.1021/acs.analchem.9b03119 ]
References 1. Liu Jianming, Zhang Han, Xu Yingying, Meng Hao, Zeng An-Ping. (2023) Turn air-captured CO2 with methanol into amino acid and pyruvate in an ATP/NAD(P)H-free chemoenzymatic system. Nature Communications, 14 (1): (1-12). [PMID:37188719 ] [10.1038/s41467-023-38490-w ] 2. Junli Guo, Lingling Yang, Huijie Xu, Chenxi Zhao, Zhenqing Dai, Zhida Gao, Yanyan Song. (2019) Biomineralization-Driven Ion Gate in TiO2 Nanochannel Arrays for Cell H2S Sensing. ANALYTICAL CHEMISTRY, 91 (21): (13746–13751). [PMID:31559823 ] [10.1021/acs.analchem.9b03119 ]
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