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Pyridoxal hydrochloride - 99%, high purity , CAS No.65-22-5

  • ≥99%
Item Number
P111170
Grouped product items
SKUSizeAvailabilityPrice Qty
P111170-1g
1g
In stock
$20.90
P111170-5g
5g
In stock
$45.90
P111170-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$134.90
P111170-100g
100g
In stock
$485.90

Basic Description

SynonymsPYRIDOXAL HYDROCHLORIDE|65-22-5|Pyridoxal HCl|3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride|2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine hydrochloride|MFCD00012809|3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde, hydro
Specifications & Purity≥99%
Biochemical and Physiological MechanismsPyridoxal hydrochloride interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.Pyridoxal hydrochloride is an endogenous metabolite.
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Pyridoxal hydrochloride is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements.

Associated Targets

CAD Tchem CAD protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRIM24 Tchem Transcription intermediary factor 1-alpha 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRIM33 Tchem E3 ubiquitin-protein ligase TRIM33 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;hydrochloride
INCHI InChI=1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H
InChi Key FCHXJFJNDJXENQ-UHFFFAOYSA-N
Canonical SMILES CC1=NC=C(C(=C1O)C=O)CO.Cl
Isomeric SMILES CC1=NC=C(C(=C1O)C=O)CO.Cl
WGK Germany 2
RTECS UV1225000
PubChem CID 6171
Molecular Weight 203.62
Beilstein 3656994
Reaxy-Rn 3656994

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

15 results found

Lot NumberCertificate TypeDateItem
I2212224Certificate of AnalysisJun 19, 2024 P111170
I2212225Certificate of AnalysisJun 19, 2024 P111170
I2212226Certificate of AnalysisJun 19, 2024 P111170
I2212227Certificate of AnalysisJun 12, 2024 P111170
B2419387Certificate of AnalysisJan 30, 2024 P111170
B2419389Certificate of AnalysisJan 30, 2024 P111170
B2419390Certificate of AnalysisJan 30, 2024 P111170
I2321834Certificate of AnalysisSep 14, 2023 P111170
I2321889Certificate of AnalysisSep 14, 2023 P111170
I2321896Certificate of AnalysisSep 14, 2023 P111170
K2127658Certificate of AnalysisSep 11, 2023 P111170
K2127659Certificate of AnalysisSep 11, 2023 P111170
K2127660Certificate of AnalysisSep 11, 2023 P111170
B2120145Certificate of AnalysisNov 14, 2022 P111170
B2120144Certificate of AnalysisNov 14, 2022 P111170

more

Chemical and Physical Properties

SensitivityLight Sensitive,Air Sensitive;Hygroscopic
Melt Point(°C)172°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS UV1225000
Reaxy-Rn 3656994
Merck Index 7978

Related Documents

References

1. Masoud Vedadi,Frank H Niesen,Abdellah Allali-Hassani,Oleg Y Fedorov,Patrick J Finerty,Gregory A Wasney,Ron Yeung,Cheryl Arrowsmith,Linda J Ball,Helena Berglund,Raymond Hui,Brian D Marsden,Pär Nordlund,Michael Sundstrom,Johan Weigelt,Aled M Edwards.  (2006-10-13)  Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination..  Proceedings of the National Academy of Sciences of the United States of America,  103  ((43)): (15835-15840).  [PMID:17035505]
2. Eric Nurit,Bernard Lyan,Agnès Piquet,Gérard Branlard,Estelle Pujos-Guillot.  (2015-02-24)  Development of a LC-MS/MS method for the simultaneous screening of seven water-soluble vitamins in processing semi-coarse wheat flour products..  Analytical and bioanalytical chemistry,  407  ((12)): (3471-3479).  [PMID:25701425]
3. Lucia Carrano,Monica Abbondi,Paola Turconi,Gianpaolo Candiani,Flavia Marinelli.  (2015-09-09)  A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening..  BioMed research international,  2015  (419383-419383).  [PMID:26346738]
4. Bachmann, et al..  (2021)  Development of a LC-MS/MS method using stable isotope dilution for the quantification of individual B6 vitamers in fruits, vegetables, and cereals..  Analytical and Bioanalytical Chemistry,  412  (7237-7252).  [PMID:32797304]
5. Ashish A Kawale,Björn M Burmann.  (2021-11-12)  Characterization of backbone dynamics using solution NMR spectroscopy to discern the functional plasticity of structurally analogous proteins..  STAR protocols,  ((4)): (100919-100919).  [PMID:34761231]
6. Toshio Iwasaki,Rimma I Samoilova,Asako Kounosu,Daijiro Ohmori,Sergei A Dikanov.  (2009-09-10)  Continuous-wave and pulsed EPR characterization of the [2Fe-2S](Cys)3(His)1 cluster in rat MitoNEET..  Journal of the American Chemical Society,  131  ((38)): (13659-13667).  [PMID:19736979]

Solution Calculators