R-7128 - ≥98%, high purity , Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor, CAS No.940908-79-2, Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor

Item Number

R127536

Grouped product items
SKU	Size	Availability	Price
R127536-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$71.90
R127536-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$221.90
R127536-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$305.90
R127536-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$418.90
R127536-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$791.90

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Basic Description

Synonyms	Mericitabine\|940908-79-2\|R-7128\|R7128\|PSI 6130 diisobutyrate\|RG7128\|RO-5024048\|RG 7128\|3',5'-Diisobutyryl PSI 6130\|R 7128\|RG-7128\|TA63JX8X52\|2'-Deoxy-2'-fluoro-2'-C-methylcytidine diisobutyrate\|RO5024048\|(2R,3R,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	R-7128(RG 7128; Mericitabine; PSI 6130 diisobutyrate)is RNA-directed RNA polymerase (NS5B) inhibitor treatment of hepatitis C virus infection. R-7128 (RG 7128; Mericitabine; PSI 6130 diisobutyrate) is useful for antiviral agents
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Product Description	Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.

Names and Identifiers

IUPAC Name	[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-fluoro-4-methyl-3-(2-methylpropanoyloxy)oxolan-2-yl]methyl 2-methylpropanoate
INCHI	InChI=1S/C18H26FN3O6/c1-9(2)14(23)26-8-11-13(28-15(24)10(3)4)18(5,19)16(27-11)22-7-6-12(20)21-17(22)25/h6-7,9-11,13,16H,8H2,1-5H3,(H2,20,21,25)/t11-,13-,16-,18-/m1/s1
InChi Key	MLESJYFEMSJZLZ-MAAOGQSESA-N
Canonical SMILES	CC(C)C(=O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)(C)F)OC(=O)C(C)C
Isomeric SMILES	CC(C)C(=O)OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=NC2=O)N)(C)F)OC(=O)C(C)C
PubChem CID	16122663
Molecular Weight	399.41

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
E2431362	Certificate of Analysis	Feb 04, 2024	R127536
E2431374	Certificate of Analysis	Feb 04, 2024	R127536
E2431375	Certificate of Analysis	Feb 04, 2024	R127536
E2431376	Certificate of Analysis	Feb 04, 2024	R127536
E2431390	Certificate of Analysis	Feb 04, 2024	R127536
E2431391	Certificate of Analysis	Feb 04, 2024	R127536
E2431402	Certificate of Analysis	Feb 04, 2024	R127536
E2431442	Certificate of Analysis	Feb 04, 2024	R127536
E2431443	Certificate of Analysis	Feb 04, 2024	R127536
E2431444	Certificate of Analysis	Feb 04, 2024	R127536

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Basic Description